Mercurio A, Altieri M, Saraceni V M, Paolucci T, Lenzi G L
Department of Neurological and Psychiatric Sciences, Sapienza University of Rome, Viale dell'Università 30, 00185 Rome, Italy.
Case Rep Med. 2013;2013:747431. doi: 10.1155/2013/747431. Epub 2013 Jan 3.
Sjögren syndrome (SS) is an autoimmune disease of the exocrine glands, characterized by focal lymphocytic infiltration and destruction of these glands. Neurologic complications are quite common, mainly involving the peripheral nervous system (PNS). The most common central nervous system (CNS) manifestations are myelopathy and microcirculation vasculitis. However, specific diagnostic criteria for CNS SS are still lacking. We report two cases of primary SS in which the revealing symptom was cerebral venous thrombosis (CVT) in the absence of genetic or acquired thrombophilias.
干燥综合征（SS）是一种外分泌腺的自身免疫性疾病，其特征是这些腺体出现局灶性淋巴细胞浸润和破坏。神经并发症相当常见，主要累及周围神经系统（PNS）。最常见的中枢神经系统（CNS）表现是脊髓病和微循环血管炎。然而，CNS型SS的具体诊断标准仍然缺乏。我们报告了两例原发性SS病例，其首发症状为脑静脉血栓形成（CVT），且不存在遗传性或获得性血栓形成倾向。
