Lang Yue, Zhang Weiguanliu, Wu Xiujuan, Deng Fang, Cui Li
Department of Neurology, Neuroscience Center, The First Hospital of Jilin University, Jilin University, Changchun, China.
Ann Indian Acad Neurol. 2020 Jan-Feb;23(1):110-112. doi: 10.4103/aian.AIAN_224_18.
Cerebral venous sinus thrombosis (CVST) is a cerebrovascular disease that is caused by a number of factors, including hypercoagulability and vessel wall damage. Sjögren's syndrome (SS) is a chronic inflammatory autoimmune disease characterized by lymphocyte infiltration of the exocrine glands. CVST could be caused by autoimmune diseases. According to previous reports, the most frequently reported autoimmune diseases which could cause CVST are systemic lupus erythematosus and antiphospholipid syndrome. Reports of SS leading to CVST are scarce. Here, we present a case of a 51-year-old woman who was diagnosed with SS-induced CVST. We tease out knowledge about the pathogenesis, feature of clinic symptom, treatment, and prognosis of SS-associated CVST, and illustrates how a detailed patient history can contribute to an accurate diagnosis.
脑静脉窦血栓形成（CVST）是一种由多种因素引起的脑血管疾病，这些因素包括高凝状态和血管壁损伤。干燥综合征（SS）是一种慢性炎症性自身免疫性疾病，其特征是外分泌腺淋巴细胞浸润。CVST可能由自身免疫性疾病引起。根据以往报告，最常报告的可导致CVST的自身免疫性疾病是系统性红斑狼疮和抗磷脂综合征。关于SS导致CVST的报告很少。在此，我们报告一例51岁女性被诊断为SS诱发的CVST。我们梳理了关于SS相关性CVST的发病机制、临床症状特征、治疗及预后的知识，并说明了详细的患者病史如何有助于准确诊断。
