Chaudhary Shyam Chand, Sawlani Kamal Kumar, Arora Rahul, Kumar Vivek
Department of Medicine, KG Medical University (Erstwhile CSMMU), Lucknow, Uttar Pradesh, India.
BMJ Case Rep. 2013 Feb 20;2013:bcr2012007144. doi: 10.1136/bcr-2012-007144.
Infective endocarditis is the most common and dangerous form of endovascular infection. Fungal endocarditis especially of native valve is rare with Candida albicans being the causative organism in one-fourth of such cases. Diagnosis of such cases is further complicated if blood cultures are sterile, vegetations are not initially seen on echocardiogram and patient presents with non-specific symptoms. We hereby report a patient with native valve fungal endocarditis, treated successfully with voriconazole.
感染性心内膜炎是血管内感染最常见且最危险的形式。真菌性心内膜炎,尤其是自体瓣膜真菌性心内膜炎较为罕见,白色念珠菌是此类病例中四分之一的致病微生物。如果血培养无菌、超声心动图最初未发现赘生物且患者表现为非特异性症状,那么此类病例的诊断会更加复杂。我们在此报告一例自体瓣膜真菌性心内膜炎患者,经伏立康唑成功治疗。