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免疫功能正常的患者发生正常主动脉瓣的心内膜炎。

endocarditis involving a normal native aortic valve in an immunocompetent patient.

机构信息

Department of Internal Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, USA

Department of Internal Medicine, University of Toledo, Toledo, Ohio, USA.

出版信息

BMJ Case Rep. 2020 Nov 17;13(11):e236902. doi: 10.1136/bcr-2020-236902.

Abstract

Fungal endocarditis, specifically from species, is a rare but serious infection with a high mortality rate. Most cases occur in bioprosthetic or mechanical valves and are uncommon in native, structurally normal valves. When endocarditis is detected and appropriate treatment is initiated earlier, there is an improvement in mortality. While the recommendation is usually to treat with a combination of surgery and antifungal medications, patient comorbidities may limit treatment options.

摘要

真菌感染性心内膜炎,特别是由 引起的感染,是一种罕见但严重的疾病,死亡率很高。大多数病例发生在生物假体或机械瓣膜上,而在原生、结构正常的瓣膜中则不常见。当发现真菌性心内膜炎并及早开始适当的治疗时,死亡率会有所改善。虽然通常建议采用手术和抗真菌药物联合治疗,但患者的合并症可能会限制治疗选择。

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