National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD 20892, United States.
Curr Opin Neurobiol. 2013 Aug;23(4):639-48. doi: 10.1016/j.conb.2013.01.002. Epub 2013 Feb 21.
Through sequential waves of drug-induced neurochemical stimulation, addiction co-opts the brain's neuronal circuits that mediate reward, motivation to behavioral inflexibility and a severe disruption of self-control and compulsive drug intake. Brain imaging technologies have allowed neuroscientists to map out the neural landscape of addiction in the human brain and to understand how drugs modify it.
通过药物诱导的神经化学刺激的连续波，成瘾会利用大脑中调节奖励、动机、行为灵活性以及严重破坏自我控制和强迫性药物摄入的神经元回路。脑成像技术使神经科学家能够绘制出人类大脑中成瘾的神经图谱，并了解药物如何改变它。
