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[农药中毒时胺氧化酶活性变化的特征]

[Characteristics of changes in amine oxidase activity during pesticide poisoning].

作者信息

Zeĭnalov T A, Gorkin V Z

出版信息

Vopr Med Khim. 1990 Jan-Feb;36(1):78-81.

PMID:2343583
Abstract

In persons professionally contacting with pesticides for a long time activity of membrane-bound monoamine oxidases (MAO) was statistically distinctly higher (about 2-fold) in blood thrombocytes, while activity of soluble amine oxidase (AO) was considerably lower (about 5-fold) in blood serum and plasma as compared with persons who did not have prolonged contact with pesticides. These data suggest that estimation of MAO activity in thrombocytes and of AO activity in blood serum may be used for hygienic evaluation of criteria involved in the conception "normal state--prepathology".

摘要

长期从事农药接触工作的人员,其血小扳中膜结合单胺氧化酶(MAO)的活性在统计学上显著较高(约为2倍),而血清和血浆中可溶性胺氧化酶(AO)的活性与未长期接触农药的人员相比则显著较低(约为5倍)。这些数据表明,血小板中MAO活性和血清中AO活性的测定可用于对“正常状态-病理前期”概念所涉及标准的卫生学评价。

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