Cardiology, University of Ottawa, Ottawa, ON, Canada.
J Nucl Cardiol. 2013 Jun;20(3):358-66. doi: 10.1007/s12350-013-9674-6. Epub 2013 Feb 22.
We compared a dedicated cardiac camera with a traditional system for left ventricular (LV) functional measurements using gated blood-pool imaging.
24-frame gated planar images were obtained from 48 patients in an LAO orientation for 6M counts/view on a standard gamma camera. Immediately thereafter, 24-frame ECG-gated data were obtained for 8 minutes on a dedicated cardiac SPECT camera. The gated SPECT image volumes were iteratively reconstructed and then transferred offline. In-house software was used to reproject the images into a 24-frame gated planar format. Both the original and the reprojected gated planar datasets were analyzed using semiautomated software to determine ejection fraction (EF), ventricular volume (end diastolic volume, EDV), peak ejection rate (PER), and peak filling rate (PFR).
The difference in EF values averaged 0.4% ± 4.4%. The correlation in EF was r ≥ 0.94 (P < .01) with a linear regression slope of 0.98. Correlation of the EDV was r ≥ 0.86 (P < .01), but the volumes from the dedicated cardiac camera were smaller (linear regression slope was 0.6). Correlation of PFR and PER were r = 0.91 and r ≥ 0.83, respectively (P < .01 for both).
Reprojection of 24-frame gated blood-pool SPECT images is an effective means of obtaining LV functional measurements with a dedicated cardiac SPECT camera using standard 2D-planar analysis tools.
我们比较了专用心脏相机和传统系统，使用门控血池成像对左心室（LV）功能进行测量。
在 LAO 方位为 48 例患者获得 24 帧门控平面图像，每视图计数 6M。立即在专用心脏 SPECT 相机上获得 24 帧 ECG 门控数据 8 分钟。门控 SPECT 图像体积进行迭代重建，然后离线传输。使用内部软件将图像重新投影到 24 帧门控平面格式。使用半自动软件分析原始和重新投影的门控平面数据集，以确定射血分数（EF）、心室容积（舒张末期容积，EDV）、峰值射血率（PER）和峰值充盈率（PFR）。
EF 值的差异平均为 0.4%±4.4%。EF 的相关性 r≥0.94（P<.01），线性回归斜率为 0.98。EDV 的相关性 r≥0.86（P<.01），但专用心脏相机的体积较小（线性回归斜率为 0.6）。PFR 和 PER 的相关性分别为 r=0.91 和 r≥0.83（两者均 P<.01）。
使用标准的 2D 平面分析工具，重新投影 24 帧门控血池 SPECT 图像是一种从专用心脏 SPECT 相机获得 LV 功能测量的有效方法。
