Bisset Lazcano Juan A, Rodríguez Coto María Magdalena, Moya Hernández Maira, Ricardo Leyva Yanelys, Montada Dorta Domingo, Gato De Armas René, Pérez Insueta Omayda
Instituto de Medicina Tropical "Pedro Kourí", La Habana, Cuba.
Rev Cubana Med Trop. 2011 May-Aug;63(2):166-70.
the vector control remains the sole sustainable measure to prevent dengue transmission in which the key role goes to adulticides in case of high rates of infestation by the vector, outbreaks or dengue epidemics. Pyrethroids are the most used whereas organophosphorous chloripirifos has been occasionally used because of the cost.
to determine the effectiveness of insecticides in their commercial formulation that is applied today by the National Unit of Anti-Vector Control and Surveillance in Cuba for the control of Ae aegypti adults such as chlorpirifos (Terfos 48 CE) and pyrethroids, lambda-cyhalothrin (ICON 2.5 CE) and cypermethrin (Galgotrin 25 CE).
fifteen Ae. Aegypti strains from the 15 municipalities of La Habana province, collected in 2008, and the Rockefeller reference strain were used. The level of effectiveness of these products against the adult vector was determined through WHO-recommended bioassays.
in situ effectiveness bioassays, Terphos 48 CE was the most effective in causing 100 % mortality of all the strains, followed by Icon 2.5 CE and Galgotrin 25 CE which reached 98 % and 100 % mortality rates respectively.
the field tests showed that the insecticides currently in use in the Aedes aegypti eradication program are still highly effective in La Habana province. The combined use of chlorpirifos and pyrethroids are recommended to delay the evolution of resistance to this last group of insecticides.
病媒控制仍然是预防登革热传播的唯一可持续措施，在病媒大量滋生、暴发或登革热流行的情况下，杀虫剂在其中起着关键作用。拟除虫菊酯是使用最广泛的，而有机磷毒死蜱由于成本原因偶尔使用。
确定古巴国家病媒控制与监测单位目前用于控制埃及伊蚊成虫的商用杀虫剂配方的有效性，如毒死蜱（特福斯48 CE）以及拟除虫菊酯、高效氯氟氰菊酯（爱克宁2.5 CE）和氯氰菊酯（盖高特灵25 CE）。
使用了2008年从哈瓦那省15个市采集的15株埃及伊蚊以及洛克菲勒参考品系。通过世界卫生组织推荐的生物测定法确定这些产品对成虫病媒的有效性水平。
现场有效性生物测定中，特福斯48 CE最有效，能使所有品系的死亡率达到100%，其次是爱克宁2.5 CE和盖高特灵25 CE，死亡率分别达到98%和100%。
现场测试表明，目前在埃及伊蚊根除计划中使用的杀虫剂在哈瓦那省仍然非常有效。建议联合使用毒死蜱和拟除虫菊酯，以延缓对后一组杀虫剂抗性的演变。
