Rodríguez Coto María Magdalena, Bisset Lazcano Juan A, Moya Hernández Maira, Ricardo Leyva Yanelys, Pérez Insueta Omayda, Fuentes López Ilario, Caceres Carrera Lorenzo
Instituto de Medicina Tropical "Pedro Kouri (IPK), La Habana, Cuba.
Rev Cubana Med Trop. 2011 Jan-Apr;63(1):81-6.
In spite of the huge efforts of the Aedes aegypti eradication program in Cuba, there are still certain infestation indexes favoring the development of outbreaks or epidemics in some regions of the country. Havana province holds a leading position in this negative indicator, in which the use of insecticides plays an important role.
To evaluate the impact of the use of insecticides in the development of drug resistance by this species in Havana.
Fifteen Ae. aegypti strains from the fifteen municipalities of the province were used. They were all collected in 2008. The level of susceptibility to insecticides was measured by means of the WHO-recommended bioassays.
Sixty percent of the strains were susceptible to chlorpirifos; more resistance to pyrethroid cypermethrin was observed followed by lambdacyalothrin and cifluthrin.
The insecticide Chlorpirifos is a good candidate to be used with pyrethroids, on a rotational scheme, to delay the development of resistance to pyrethroids in Ae. aegypti vectors in Havana province.
尽管古巴在埃及伊蚊根除计划上付出了巨大努力，但该国某些地区仍存在一定的感染指数，有利于疫情或流行病的爆发。哈瓦那省在这一负面指标上处于领先地位，其中杀虫剂的使用起着重要作用。
评估在哈瓦那使用杀虫剂对该物种产生抗药性发展的影响。
使用了来自该省15个市的15株埃及伊蚊。它们均于2008年采集。通过世界卫生组织推荐的生物测定法测量对杀虫剂的易感性水平。
60%的菌株对毒死蜱敏感；观察到对拟除虫菊酯氯氰菊酯的抗性更强，其次是氯氟氰菊酯和氟氯氰菊酯。
杀虫剂毒死蜱是与拟除虫菊酯按轮换方案使用的良好候选药物，以延缓哈瓦那省埃及伊蚊病媒对拟除虫菊酯抗药性的发展。
