Romagnoli S, Romano S M, Bevilacqua S, Lazzeri C, Ciappi F, Dini D, Pratesi C, Gensini G F
Department of Cardiac and Vascular Anesthesia and Post-Surgical Intensive Care Unit, Careggi Hospital, Florence, Italy.
HSR Proc Intensive Care Cardiovasc Anesth. 2009;1(1):54-8.
Patients can show arterial pressure and cardiac index within the normal range and still be in circulatory shock if oxygen and metabolic demand is increased or blood flow distribution is altered.Lactate is produced in anaerobic environment to preserve cellular integrity and physicians use its blood concentration value as a reliable marker of tissue hypoxia and energy failure.The authors review the recent literature on the importance of mixed venous oxygen saturation (SvO(2)) as an early sign of inadequate DO(2) that precede the lactate production.
如果氧和代谢需求增加或血流分布改变，患者的动脉压和心脏指数可处于正常范围，但仍可能处于循环性休克状态。乳酸在无氧环境中产生以维持细胞完整性，医生将其血浓度值用作组织缺氧和能量衰竭的可靠标志物。作者回顾了近期关于混合静脉血氧饱和度（SvO₂）作为在乳酸产生之前氧输送（DO₂）不足的早期迹象的重要性的文献。
