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社区获得性尿路感染中表皮葡萄球菌脉冲场凝胶电泳群的时间分布。

Time-based distribution of Staphylococcus saprophyticus pulsed field gel-electrophoresis clusters in community-acquired urinary tract infections.

机构信息

Faculdade de Medicina, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.

出版信息

Mem Inst Oswaldo Cruz. 2013 Feb;108(1):73-6. doi: 10.1590/s0074-02762013000100012.

DOI:10.1590/s0074-02762013000100012
PMID:23440118
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3974321/
Abstract

The epidemiology of urinary tract infections (UTI) by Staphylococcus saprophyticus has not been fully characterised and strain typing methods have not been validated for this agent. To evaluate whether epidemiological relationships exist between clusters of pulsed field gel-electrophoresis (PFGE) genotypes of S. saprophyticus from community-acquired UTI, a cross-sectional surveillance study was conducted in the city of Rio de Janeiro, Brazil. In total, 32 (16%) female patients attending two walk-in clinics were culture-positive for S. saprophyticus. Five PFGE clusters were defined and evaluated against epidemiological data. The PFGE clusters were grouped in time, suggesting the existence of community point sources of S. saprophyticus. From these point sources, S. saprophyticus strains may spread among individuals.

摘要

尿路上皮细胞细菌感染(UTI)的流行病学尚未完全明确,且针对该病原体的菌株分型方法尚未得到验证。为了评估社区获得性 UTI 中由腐生葡萄球菌引起的脉冲场凝胶电泳(PFGE)基因型聚类之间是否存在流行病学关系,在巴西里约热内卢市进行了一项横断面监测研究。共有 32 名(16%)女性患者在两家就诊诊所中培养出腐生葡萄球菌阳性。定义了 5 个 PFGE 聚类,并针对流行病学数据进行了评估。PFGE 聚类按时间分组,提示腐生葡萄球菌存在社区性的单一感染源。这些感染源可能会导致腐生葡萄球菌菌株在人群中传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4f5/3974321/f5362ec314df/0074-0276-mioc-108-01-0073-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4f5/3974321/c1df3ffd8b27/0074-0276-mioc-108-01-0073-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4f5/3974321/a6fbbabbc7b3/0074-0276-mioc-108-01-0073-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4f5/3974321/f5362ec314df/0074-0276-mioc-108-01-0073-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4f5/3974321/c1df3ffd8b27/0074-0276-mioc-108-01-0073-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4f5/3974321/a6fbbabbc7b3/0074-0276-mioc-108-01-0073-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4f5/3974321/f5362ec314df/0074-0276-mioc-108-01-0073-gf03.jpg

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