Thornton J R, Teague R H, Low-Beer T S, Read A E
Gut. 1980 Mar;21(3):247-8. doi: 10.1136/gut.21.3.247.
The relationship of pyoderma gangrenosum and ulcerative colitis remains uncertain. We investigating 14 patients with pyoderma gangrenosum by colonoscopy with multiple biopsies. Six patients had ulcerative colitis and all of these had disease affecting the whole colon. There were no correlations between exacerbations of the colitis and the onset or course of pyoderma gangrenosum. The remaining eight patients with pyoderma gangrenosum had no other disease and they were found to be significantly older than those patients with coexisting colitis (P less than 0.002).
坏疽性脓皮病与溃疡性结肠炎之间的关系仍不明确。我们通过结肠镜检查及多次活检对14例坏疽性脓皮病患者进行了研究。6例患者患有溃疡性结肠炎,且所有这些患者的病变均累及全结肠。结肠炎的加重与坏疽性脓皮病的发作或病程之间无相关性。其余8例坏疽性脓皮病患者无其他疾病,且发现他们的年龄显著大于合并结肠炎的患者(P<0.002)。