Department of Dermatology and Venereology, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Indian J Dermatol Venereol Leprol. 2013 Mar-Apr;79(2):227-30. doi: 10.4103/0378-6323.107643.
Bowen's disease commonly presents as a solitary asymptomatic plaque involving head and neck region or lower limbs. We present a case of a sixty seven-year-old man with an itchy, oozy, crusted solitary plaque on the right ring finger of eighteen months duration with histopathology consistent with Bowen's disease. The lesion was initially treated with topical 5% imiquimod but due to relapse and inadequate response to a second course, complete surgical excision followed by full thickness skin grafting was done. Recurrence after about 6 months in the form of a small papule adjacent to the initial site was also treated with excision. This report highlights the potential of Bowen's disease to mimic more common dermatoses and a high index of suspicion, supported by histopathology, is required to diagnose and treat it without delay, which in turn may require a multimodality approach. We also reviewed the current literature on the same.
鲍文病通常表现为单发无症状斑块，累及头颈部或下肢。我们报告了一例 67 岁男性患者，其右无名指有一处 18 个月的瘙痒、渗出、结痂的孤立斑块，组织病理学符合鲍文病。病变最初用 5%咪喹莫特局部治疗，但由于复发和第二次治疗反应不足，随后进行了完全手术切除和全厚皮片移植。大约 6 个月后，在初始部位附近出现一个小丘疹，也进行了切除。本报告强调了鲍文病可能模仿更常见皮肤病的可能性，需要高度怀疑，并通过组织病理学支持，及时诊断和治疗，这反过来可能需要多模式方法。我们还回顾了同一主题的当前文献。
