Brorson Stig, Eckardt Henrik, Audigé Laurent, Rolauffs Bernd, Bahrs Christian
Department of Orthopaedic Surgery, Herlev University Hospital, Herlev, Denmark.
BMC Res Notes. 2013 Feb 25;6:69. doi: 10.1186/1756-0500-6-69.
The reporting and interpretation of data from clinical trials of proximal humeral fractures are hampered by the use of two partly incommensurable fracture classification systems: the Neer classification and the AO/OTA classification. It remains difficult to interpret and generalize results, to conduct prognostic studies, and to obtain consensus on treatment recommendations when concise definitions and a common 'fracture language' are lacking. Thus, we compared both classifications systems using primary data from large clinical studies to assess how thoroughly both systems conveyed clinically important classification information.
Classification data from each study were organized in a cross-table covering the 432 theoretically possible combinations between the 16 Neer categories and the 27 AO/OTA subgroups, and the plausibility of all observed combinations were assessed and discussed by the authors until consensus.
We analyzed primary data from 2530 observations from seven studies providing primary data from both classification systems. Thirty-five percent (151 out of 432) of the combinations were considered 'not plausible' and thirty-four percent (149 out of 432) were considered 'problematic'.
Clinically important information was lost within both classification systems. Most important, the varus/valgus distinction was not found within the Neer classification and a clear definition of displacement was lacking in the AO/OTA classification. We encourage surgeons and researches to report data from both classification systems for a more thorough description of the fracture patterns and to enable cross-checking of the coding. A suitable table for cross-checking of the coding is provided herein.
肱骨近端骨折临床试验数据的报告和解读受到两种部分不可通约的骨折分类系统的阻碍,即Neer分类系统和AO/OTA分类系统。当缺乏简洁的定义和通用的“骨折语言”时,仍然难以解释和归纳结果、进行预后研究以及就治疗建议达成共识。因此,我们使用大型临床研究的原始数据比较了这两种分类系统,以评估它们在多大程度上全面传达了具有临床重要性的分类信息。
每项研究的分类数据被整理成一个交叉表,涵盖Neer分类的16个类别与AO/OTA分类的27个亚组之间理论上可能的432种组合,作者对所有观察到的组合的合理性进行评估和讨论,直至达成共识。
我们分析了来自七项研究的2530例观察的原始数据,这些研究提供了两种分类系统的原始数据。35%(432种组合中的151种)的组合被认为“不合理”,34%(432种组合中的149种)被认为“有问题”。
两种分类系统都丢失了具有临床重要性的信息。最重要的是,Neer分类中未发现内翻/外翻的区分,AO/OTA分类中缺乏移位的明确定义。我们鼓励外科医生和研究人员报告两种分类系统的数据,以便更全面地描述骨折类型,并能够对编码进行交叉核对。本文提供了一个用于编码交叉核对的合适表格。