Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark.
BMJ Open. 2013 Feb 26;3(2). doi: 10.1136/bmjopen-2012-002259. Print 2013.
The aim of this study was to evaluate the impact of socioeconomic and clinical factors on the transitions between work, sickness absence and retirement in a cohort of Danish colorectal cancer survivors.
Register-based cohort study with up to 10 years of follow-up.
Population-based study with use of administrative health-related and socioeconomic registers.
All persons (N=4343) diagnosed with colorectal cancer in Denmark during the years 2001-2009 while they were in their working age (18-63 years) and who were part of the labour force 1 year postdiagnosis.
By the use of multistate models in Cox proportional hazards models, we analysed the HR for re-employment, sickness absence and retirement in models including clinical as well as health-related variables.
1 year after diagnosis, 62% were working and 58% continued until the end of follow-up. Socioeconomic factors were found to be associated with retirement but not with sickness absence and return to work. The risk for transition from work to sickness absence increased if the disease was diagnosed at a later stage (stage III) 1.52 (95% CI 1.21 to 1.91), not operated curatively 1.35 (95% CI 1.11 to 1.63) and with occurrence of postoperative complications 1.25 (95% CI 1.11 to 1.41). The opposite was found for the transition from sickness absence back to work.
This nationwide study of colorectal cancer patients who have survived 1 year shows that the stage of disease, general health condition of the individual, postoperative complications and the history of sickness absence and unemployment have an impact on the transition between work, sickness absence and disability pension. This leads to an increased focus on the rehabilitation process for the more vulnerable persons who have a combination of severe disease and a history of work-related problems with episodes outside the working market.
本研究旨在评估社会经济和临床因素对丹麦结直肠癌幸存者队列中工作、病假和退休之间转变的影响。
基于登记的队列研究,最长随访 10 年。
利用行政健康相关和社会经济登记处进行基于人群的研究。
2001 年至 2009 年间在丹麦被诊断患有结直肠癌的所有人员(N=4343),他们在工作年龄(18-63 岁)时处于工作状态,并且在诊断后 1 年内为劳动力的一部分。
通过使用多状态模型在 Cox 比例风险模型中,我们分析了包括临床和健康相关变量在内的模型中重新就业、病假和退休的 HR。
诊断后 1 年,62%的人在工作,58%的人一直工作到随访结束。社会经济因素与退休有关,但与病假和重返工作无关。如果疾病诊断较晚(III 期),则从工作向病假过渡的风险增加 1.52(95%CI 1.21 至 1.91),未进行根治性手术则增加 1.35(95%CI 1.11 至 1.63),术后并发症发生则增加 1.25(95%CI 1.11 至 1.41)。从病假返回到工作的情况则相反。
这项对结直肠癌存活 1 年的患者的全国性研究表明,疾病的阶段、个体的整体健康状况、术后并发症以及病假和失业的历史都会对工作、病假和残疾养老金之间的转变产生影响。这导致更多关注那些疾病严重且有与工作相关问题和离开工作市场的病史的弱势群体的康复过程。