School of Health and Related Research, University of Sheffield, Regent Court, 30 Regent St., Sheffield, S1 4DA, UK.
J Pers Disord. 2013 Jun;27(3):383-401. doi: 10.1521/pedi_2013_27_075. Epub 2013 Feb 27.
A systematic review was undertaken to assess the construct validity and responsiveness of four generic health-related quality of life (HRQL) measures in personality disorders (PDs). Ten databases were searched and reference lists scrutinized to identify relevant studies. Relevant data were extracted accordingly. A narrative synthesis was performed of the evidence on construct validity, including known groups validity (detecting differences in HRQL scores between two different groups), convergent validity (strength of association between generic HRQL), and other measures (e.g., symptom) and responsiveness (differences in generic HRQL measure scores in responders/nonresponders or correlation with changes in other measures). Ten studies were identified: six of the EQ-5D, two involving the SF-36, and another two the SF-12, but none with the SF-6D. Evidence indicated that the EQ-5D, SF-36, and SF-12 were probably valid measures with PDs. Four studies demonstrated that the EQ-5D Index was able to detect changes in patients. The authors conclude that generic HRQL measures appear appropriate for use with people with PDs in terms of psychometric performance. However, qualitative concerns remain as to whether they fully reflect the impact of the condition.
系统评价评估了四种通用健康相关生活质量（HRQL）衡量标准在人格障碍（PD）中的结构有效性和反应性。检索了十个数据库并仔细审查了参考列表，以确定相关研究。相应地提取了相关数据。对结构有效性的证据进行了叙述性综合，包括已知组有效性（检测两个不同组之间 HRQL 评分的差异）、收敛有效性（通用 HRQL 之间的关联强度）以及其他措施（例如症状）和反应性（应答者/无应答者之间通用 HRQL 衡量标准得分的差异或与其他措施变化的相关性）。确定了十项研究：六项涉及 EQ-5D，两项涉及 SF-36，另外两项涉及 SF-12，但均不涉及 SF-6D。证据表明，EQ-5D、SF-36 和 SF-12 可能是具有 PD 的有效衡量标准。四项研究表明，EQ-5D 指数能够检测到患者的变化。作者得出结论，通用 HRQL 衡量标准在心理测量性能方面似乎适用于 PD 患者。然而，仍然存在关于它们是否完全反映病情影响的定性问题。
