• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Proteomics: improving biomarker translation to modern medicine?

作者信息

Guest Paul C, Gottschalk Michael G, Bahn Sabine

机构信息

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK ; Department of Neuroscience, Erasmus Medical Centre, Rotterdam, The Netherlands.

出版信息

Genome Med. 2013 Feb 27;5(2):17. doi: 10.1186/gm421. eCollection 2013.

DOI:10.1186/gm421
PMID:23445684
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3706758/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e538/3706758/7c3777839c89/gm421-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e538/3706758/7c3777839c89/gm421-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e538/3706758/7c3777839c89/gm421-1.jpg

相似文献

1
Proteomics: improving biomarker translation to modern medicine?蛋白质组学：能否推动生物标志物转化应用于现代医学？
Genome Med. 2013 Feb 27;5(2):17. doi: 10.1186/gm421. eCollection 2013.
2
Accelerating protein biomarker discovery and translation from proteomics research for clinical utility.加速蛋白质生物标志物的发现和转化，使其从蛋白质组学研究走向临床应用。
Bioanalysis. 2020 Oct;12(20):1469-1481. doi: 10.4155/bio-2020-0198. Epub 2020 Oct 2.
3
Cancer biomarker discovery and translation: proteomics and beyond.癌症生物标志物的发现和转化：蛋白质组学及其他。
Expert Rev Proteomics. 2019 Feb;16(2):93-103. doi: 10.1080/14789450.2019.1559062. Epub 2018 Dec 24.
4
[Proteomics for biomarker development toward personalized medicine].用于个性化医疗生物标志物开发的蛋白质组学
Rinsho Byori. 2012 Jul;60(7):644-9.
5
Advancing translational research and precision medicine with targeted proteomics.通过靶向蛋白质组学推进转化研究和精准医学。
J Proteomics. 2018 Oct 30;189:1-10. doi: 10.1016/j.jprot.2018.02.021. Epub 2018 Feb 22.
6
Targeted and Untargeted Proteomics Approaches in Biomarker Development.靶向和非靶向蛋白质组学方法在生物标志物开发中的应用。
Proteomics. 2020 May;20(9):e1900029. doi: 10.1002/pmic.201900029. Epub 2020 Jan 30.
7
From proteomics research to clinical practice.从蛋白质组学研究到临床实践。
Expert Rev Proteomics. 2009 Jun;6(3):235-8. doi: 10.1586/epr.09.14.
8
The Emerging Role of Proteomics in Precision Medicine: Applications in Neurodegenerative Diseases and Neurotrauma.蛋白质组学在精准医学中的新兴作用：在神经退行性疾病和神经创伤中的应用
Adv Exp Med Biol. 2017;1007:59-70. doi: 10.1007/978-3-319-60733-7_4.
9
Mass spectrometry: A platform for biomarker discovery and validation for Alzheimer's and Parkinson's diseases.质谱分析：阿尔茨海默病和帕金森病生物标志物发现和验证的平台。
J Neurochem. 2019 Nov;151(4):397-416. doi: 10.1111/jnc.14635. Epub 2019 Jan 31.
10
Application of Multiplex Biomarker Approaches to Accelerate Drug Discovery and Development.多重生物标志物方法在加速药物发现与开发中的应用。
Methods Mol Biol. 2017;1546:3-17. doi: 10.1007/978-1-4939-6730-8_1.

引用本文的文献

1
The Future of Biomarkers in Veterinary Medicine: Emerging Approaches and Associated Challenges.兽医学中生物标志物的未来：新兴方法及相关挑战
Animals (Basel). 2022 Aug 26;12(17):2194. doi: 10.3390/ani12172194.
2
Comprehensive Library Generation for Identification and Quantification of Endometrial Cancer Protein Biomarkers in Cervico-Vaginal Fluid.用于鉴定和定量宫颈阴道液中子宫内膜癌蛋白质生物标志物的综合文库生成
Cancers (Basel). 2021 Jul 28;13(15):3804. doi: 10.3390/cancers13153804.
3
GYNOCARE Update: Modern Strategies to Improve Diagnosis and Treatment of Rare Gynecologic Tumors—Current Challenges and Future Directions.

本文引用的文献

1
Proteomic approaches to the discovery of cancer biomarkers for early detection and personalized medicine.蛋白质组学方法在癌症生物标志物的发现中的应用，用于早期检测和个体化医疗。
Jpn J Clin Oncol. 2013 Feb;43(2):103-9. doi: 10.1093/jjco/hys200. Epub 2012 Dec 16.
2
Tools for protein-protein interaction network analysis in cancer research.癌症研究中蛋白质-蛋白质相互作用网络分析的工具。
Clin Transl Oncol. 2012 Jan;14(1):3-14. doi: 10.1007/s12094-012-0755-9.
3
Clinical application of tumour markers: a review.肿瘤标志物的临床应用：综述
妇科护理最新进展：改善罕见妇科肿瘤诊断与治疗的现代策略——当前挑战与未来方向
Cancers (Basel). 2021 Jan 27;13(3):493. doi: 10.3390/cancers13030493.
4
Identification of potential oxidative stress biomarkers for spinal cord injury in erythrocytes using mass spectrometry.利用质谱法鉴定红细胞中脊髓损伤的潜在氧化应激生物标志物
Neural Regen Res. 2021 Jul;16(7):1294-1301. doi: 10.4103/1673-5374.301487.
5
ProtRank: bypassing the imputation of missing values in differential expression analysis of proteomic data.ProtRank：绕过蛋白质组学数据差异表达分析中缺失值的推断。
BMC Bioinformatics. 2019 Nov 9;20(1):563. doi: 10.1186/s12859-019-3144-3.
6
Proteomic Biomarkers for the Detection of Endometrial Cancer.用于检测子宫内膜癌的蛋白质组学生物标志物
Cancers (Basel). 2019 Oct 16;11(10):1572. doi: 10.3390/cancers11101572.
7
A biological network-based regularized artificial neural network model for robust phenotype prediction from gene expression data.一种基于生物网络的正则化人工神经网络模型，用于从基因表达数据中进行稳健的表型预测。
BMC Bioinformatics. 2017 Dec 19;18(1):565. doi: 10.1186/s12859-017-1984-2.
8
Urinary metabolites in patients undergoing coronary catheterization via the radial versus femoral artery approach.经桡动脉与股动脉途径行冠状动脉导管插入术患者的尿液代谢产物
Proc (Bayl Univ Med Cent). 2017 Oct;30(4):404-409. doi: 10.1080/08998280.2017.11930207.
9
Elucidating Host-Pathogen Interactions Based on Post-Translational Modifications Using Proteomics Approaches.基于蛋白质组学方法通过翻译后修饰阐明宿主-病原体相互作用
Front Microbiol. 2015 Nov 20;6:1313. doi: 10.3389/fmicb.2015.01312. eCollection 2015.
10
Cholinesterases as biomarkers for parasympathetic dysfunction and inflammation-related disease.胆碱酯酶作为副交感神经功能障碍和炎症相关疾病的生物标志物。
J Mol Neurosci. 2014 Jul;53(3):298-305. doi: 10.1007/s12031-013-0176-4. Epub 2013 Nov 20.
East Afr Med J. 2009 Dec;86(12 Suppl):S76-83. doi: 10.4314/eamj.v86i12.62909.
4
Developing predictive CSF biomarkers-a challenge critical to success in Alzheimer's disease and neuropsychiatric translational medicine.开发具有预测性的脑脊液生物标志物——这是阿尔茨海默病和神经精神转化医学取得成功的关键挑战。
Biochem Pharmacol. 2011 Jun 15;81(12):1422-34. doi: 10.1016/j.bcp.2011.01.021. Epub 2011 Feb 3.
5
Report of the task force on designing clinical trials in early (predementia) AD.早期（痴呆前）AD 临床试验设计工作组报告。
Neurology. 2011 Jan 18;76(3):280-6. doi: 10.1212/WNL.0b013e318207b1b9. Epub 2010 Dec 22.
6
Proteomics beyond proteomics: toward clinical applications.蛋白质组学超越蛋白质组学：迈向临床应用。
Curr Opin Oncol. 2011 Jan;23(1):77-82. doi: 10.1097/CCO.0b013e32834179c1.
7
How many drug targets are there?有多少种药物靶点？
Nat Rev Drug Discov. 2006 Dec;5(12):993-6. doi: 10.1038/nrd2199.
8
Process map proposal for the validation of genomic biomarkers.用于验证基因组生物标志物的过程图提案。
Pharmacogenomics. 2006 Jul;7(5):773-82. doi: 10.2217/14622416.7.5.773.
9
Biomarkers and surrogate endpoints: preferred definitions and conceptual framework.生物标志物与替代终点：首选定义及概念框架
Clin Pharmacol Ther. 2001 Mar;69(3):89-95. doi: 10.1067/mcp.2001.113989.
10
HER-2/neu as a predictive marker of response to breast cancer therapy.HER-2/neu作为乳腺癌治疗反应的预测标志物。
Breast Cancer Res Treat. 1998;52(1-3):65-77. doi: 10.1023/a:1006111117877.