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[长期透析后肾脏的计算机断层扫描]

[Computer tomography of the kidneys after long-term dialysis].

作者信息

Srp A, Merta M, Sulková S

机构信息

Radiologická klinika FN, Praha.

出版信息

Cesk Radiol. 1990 Jan;44(1):19-25.

PMID:2344651
Abstract

In patients with chronic kidney failure in the long-term dialysis programme multiple minute cysts frequently develop in the shrunken kidneys. In addition to the cysts, in 20% of patients there are also multiple kidney tumours causing severe complications. In most cases the clinical picture of the disease is insignificant, hematuria being the most frequent manifestation. The authors present their cohort of 21 patients with irreversible kidney failure, who have been examined by computer tomography in the 1986-1987 years. The mean period of dialysis programme was 5.7 years, chronic glomerulonephritis and interstitial nephritis being the basic disease. The patient were, according to the results of computer tomography, divided into four groups: 1. the presence of cysts or tumours was not demonstrated, 2. multiple cysts were found in bilateral localization, 3. less than 3 cysts were found, 4. there was a kidney tumour. A factor causing the development of the cysts has not yet been identified. It is presumed that the disease is caused by a biologically active substance which is not efficiently dialyzed. On the basis of the present work the authors recommend the aimed examination of the kidneys in patients at the stage of chronic kidney insufficiency and particularly in patients subjected to dialysis for long period of time. The recommended examination is by computer tomography and the attention should be centered to possible occurrence of acquired cystic disease of kidney tumours.

摘要

在长期透析项目中的慢性肾衰竭患者,萎缩的肾脏中经常会出现多个微小囊肿。除囊肿外,20%的患者还存在多个肾肿瘤,可引发严重并发症。在大多数情况下,该病的临床表现不明显,血尿是最常见的表现。作者介绍了他们的21例不可逆肾衰竭患者队列,这些患者在1986 - 1987年期间接受了计算机断层扫描检查。透析项目的平均时长为5.7年,基本疾病为慢性肾小球肾炎和间质性肾炎。根据计算机断层扫描结果,患者被分为四组:1. 未发现囊肿或肿瘤;2. 双侧发现多个囊肿;3. 发现少于3个囊肿;4. 存在肾肿瘤。导致囊肿形成的因素尚未明确。据推测,该病由一种不能有效通过透析清除的生物活性物质引起。基于目前的研究工作,作者建议对慢性肾功能不全阶段的患者,尤其是长期接受透析的患者进行针对性的肾脏检查。推荐的检查方法是计算机断层扫描,应重点关注肾肿瘤获得性囊肿疾病的可能发生情况。

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