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重新打开窗口:调控大脑发育的关键期

Re-opening Windows: Manipulating Critical Periods for Brain Development.

作者信息

Hensch Takao K, Bilimoria Parizad M

出版信息

Cerebrum. 2012 Jul;2012:11. Epub 2012 Aug 29.

PMID:23447797
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3574806/
Abstract

The brain acquires certain skills-from visual perception to language-during critical windows, specific times in early life when the brain is actively shaped by environmental input. Scientists like Takao K. Hensch are now discovering pathways in animal models through which these windows might be re-opened in adults, thus re-awakening a brain's youth-like plasticity. Such research has implications for brain injury repair, sensory recovery, and neurodevelopmental disorder treatment. In addition, what we know today about these critical windows of development already has enormous implications for social and educational policy.

摘要

大脑在关键期获得某些技能——从视觉感知到语言——关键期是生命早期的特定时期,此时大脑会受到环境输入的积极塑造。像高尾健(Takao K. Hensch)这样的科学家现在正在动物模型中发现一些途径,通过这些途径,这些关键期可能在成年后重新开启,从而重新唤醒大脑类似幼年时的可塑性。此类研究对脑损伤修复、感觉恢复和神经发育障碍治疗具有重要意义。此外,我们如今对这些关键发育期的了解已经对社会和教育政策产生了巨大影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a057/3574806/07c8caac4d8e/cer-11-12-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a057/3574806/befb7bee76a1/cer-11-12-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a057/3574806/3e414ab31cc4/cer-11-12-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a057/3574806/07c8caac4d8e/cer-11-12-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a057/3574806/befb7bee76a1/cer-11-12-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a057/3574806/3e414ab31cc4/cer-11-12-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a057/3574806/07c8caac4d8e/cer-11-12-g003.jpg

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