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揭开不良妊娠结局动物模型的神秘面纱：从 bench 到 bedside。

Demystifying animal models of adverse pregnancy outcomes: touching bench and bedside.

机构信息

Department of Obstetrics, Gynecology and Reproductive Sciences, University of Vermont College of Medicine, Burlington, VT, USA.

出版信息

Am J Reprod Immunol. 2013 Jun;69(6):567-84. doi: 10.1111/aji.12102. Epub 2013 Feb 28.

DOI:10.1111/aji.12102
PMID:23448345
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4301576/
Abstract

This represents an overview of the use of animal models to study the adverse pregnancy outcomes seen in humans. The purpose is to entice clinicians to utilize some of this information to seek out the literature and have more meaningful and profitable discussions with their academic colleagues and enhance transdisciplinary research in reproductive health.

摘要

这代表了对用于研究人类不良妊娠结局的动物模型的使用的概述。其目的是吸引临床医生利用这些信息寻找文献，并与他们的学术同行进行更有意义和有益的讨论，加强生殖健康的跨学科研究。

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本文引用的文献

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Comparative analysis of genome sequences of the Th2 cytokine region of rabbit (Oryctolagus cuniculus) with those of nine different species.兔（穴兔）Th2细胞因子区域基因组序列与九个不同物种基因组序列的比较分析。
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Plant MicroRNA Prediction by Supervised Machine Learning Using C5.0 Decision Trees.使用C5.0决策树通过监督式机器学习预测植物微小RNA
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Myometrial immune cells contribute to term parturition, preterm labour and post-partum involution in mice.子宫肌层免疫细胞有助于小鼠的足月分娩、早产和产后子宫复旧。
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Medical termination of pregnancy in cynomolgus macaques.食蟹猕猴的人工流产
J Med Primatol. 2012 Dec;41(6):394-402. doi: 10.1111/jmp.12019. Epub 2012 Oct 18.
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Effect of 30% nutrient restriction in the first half of gestation on maternal and fetal baboon serum amino acid concentrations.妊娠前半期 30%营养素限制对母猴及胎猴血清氨基酸浓度的影响。
Br J Nutr. 2013 Apr 28;109(8):1382-8. doi: 10.1017/S0007114512003261. Epub 2012 Oct 9.
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Pregnancy imprints regulatory memory that sustains anergy to fetal antigen.妊娠使调节性记忆得以形成，从而维持对胎儿抗原的不应答状态。
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Skin shedding and tissue regeneration in African spiny mice (Acomys).非洲刺毛鼠（Acomys）的皮肤脱落与组织再生。
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Practice variation in late-preterm deliveries: a physician survey.晚期早产儿分娩中的实践差异：一项医师调查。
J Perinatol. 2013 May;33(5):347-51. doi: 10.1038/jp.2012.119. Epub 2012 Sep 27.