Cankaya Cem, Bozkurt Murat, Ulutas Ozkan
Universal Hospital, Department of Ophthalmology, Malatya, Turkey.
Semin Ophthalmol. 2013 Mar;28(2):103-11. doi: 10.3109/08820538.2012.760628.
ABSTRACT Purpose: To evaluate whether there are alterations in total macular volume (TMV) and foveal retinal thickness (FT) values during pregnancy.
This study included 60 healthy pregnant women in their first, second, and third trimester (groups 1, 2, and 3) and 20 nonpregnant women (group 4). TMV and FT values were measured by optical coherence tomography (OCT) in each group.
Mean TMV was 1.43 ± 0.56 mm(3), 1.88 ± 0.54 mm(3), 2.04 ± 0.66 mm(3) and 1.35 ± 0.41 mm(3) in groups 1, 2, 3, and 4, respectively. Mean FT was 199.20 ± 64.35 µ, 274.35 ± 67.45 µ, 287.95 ± 95.50 µ and 192.100 ± 58.61 µ in groups 1, 2, 3, and 4, respectively. There was statistical significance among group 1-2 (p1 = 0.014, p2 = 0.001), group 1-3 (p1 = 0.003, p2 = 0.002), group 2-4 (p1 = 0.001, p2 = 0.001), and group 3-4 (p1 = 0.001, p2 = 0.001) for both TMV and FT, respectively.
The increase of fluid in the body, in particular in the second and last trimester, may cause an increase of TMV and FT.
摘要 目的：评估孕期黄斑总体积（TMV）和中央凹视网膜厚度（FT）值是否存在变化。
本研究纳入60名处于孕早期、孕中期和孕晚期的健康孕妇（第1、2、3组）以及20名非孕妇（第4组）。每组均通过光学相干断层扫描（OCT）测量TMV和FT值。
第1、2、3、4组的平均TMV分别为1.43±0.56mm³、1.88±0.54mm³、2.04±0.66mm³和1.35±0.41mm³。第1、2、3、4组的平均FT分别为199.20±64.35µ、274.35±67.45µ、287.95±95.50µ和192.100±58.61µ。TMV和FT在第1 - 2组（p1 = 0.014，p2 = 0.001）、第1 - 3组（p1 = 0.003，p2 = 0.002）、第2 - 4组（p1 = 0.001，p2 = 0.001）和第３ - 4组（p1 = 0.001，p2 = 0.001）之间分别具有统计学意义。
体内液体增加，尤其是在孕中期和孕晚期，可能导致TMV和FT增加。
