Yang Zhi-Gang, Wen Xiu-Feng, Li Yong-Hai, Matsuzaki Keiichi, Kitanaka Susumu
School of Pharmacy, Nihon University, Funabashi, Chiba, Japan.
Chem Pharm Bull (Tokyo). 2013;61(3):279-85. doi: 10.1248/cpb.c12-00835.
Three new flavonol glycosides, hippophaeosides A-C (1-3), together with 27 known constituents, were isolated from Hippophae rhamnoides L. leaves. Their structures were determined by spectroscopic analyses. Their inhibitory activities on 3T3-L1 preadipocyte differentiation and triglyceride accumulation in maturing adipocytes, and nitric oxide production in RAW264.7 cells were examined.
从沙棘叶中分离出三种新的黄酮醇苷，沙棘苷A-C（1-3），以及27种已知成分。通过光谱分析确定了它们的结构。检测了它们对3T3-L1前脂肪细胞分化、成熟脂肪细胞中甘油三酯积累以及RAW264.7细胞中一氧化氮产生的抑制活性。
