Sood Rajeev, Khattar Nikhil, Nayyar Rishi, Kathuria Sachin, Narang Vineet, Kaushal Devashish
Department of Urology, PGIMER & Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Indian J Urol. 2012 Oct;28(4):418-23. doi: 10.4103/0970-1591.105754.
Radical perineal prostatectomy was the first surgery described for prostatic carcinoma (Young, 1904) but it lost its eminent status after Walsh's description in 1982 of anatomic radical retropubic prostatectomy followed by the enthusiasm in laparoscopy and now robotics. It made resurgence after it was realized in early 1990s that the pelvic lymph node dissection is needed only in selected cases. Last decade witnessed over 80 publications addressing the results and advances in the perineal approach. Strangely, centres from the subcontinent have chosen to ignore this resurgence. We describe our early experience with the technique in 35 patients and present the case for its more widespread usage.
Thirty five patients of clinically localized carcinoma prostate were operated by perineal route in our institution from December 2006 onwards. All patients had serum prostate specific antigen levels less than 10 ng/ml.
Operating time was 2 to 3.5 hours (mean 2.5 hours). Rectal injury occurred in three patients but was closed primarily in all and none required a colostomy. Mean duration of hospital stay was four days. The disease was organ confined in 25(71%). Positive margins were seen in 5(14%) patients. Biochemical recurrence occurred in 17% patients at one year. Seventy six percent patients had achieved continence at one year.
As the world is taking note of radical perineal prostatectomy again, with a very small learning curve, minimal invasion and good oncological control urologists from Indian subcontinent should also embrace this procedure in view of the relative limited resources available.
根治性会阴前列腺切除术是最早描述的前列腺癌手术(扬,1904年),但在1982年沃尔什描述解剖性根治性耻骨后前列腺切除术之后,它失去了突出地位,随后腹腔镜手术和现在的机器人手术兴起。在20世纪90年代初人们认识到仅在特定病例中需要盆腔淋巴结清扫术后,它又重新兴起。过去十年有80多篇关于会阴入路手术结果和进展的出版物。奇怪的是,来自次大陆的中心却选择忽视这种复兴。我们描述了我们在35例患者中应用该技术的早期经验,并提出更广泛应用该技术的理由。
从2006年12月起,我们机构对35例临床局限性前列腺癌患者采用会阴途径进行手术。所有患者血清前列腺特异性抗原水平均低于10 ng/ml。
手术时间为2至3.5小时(平均2.5小时)。3例患者发生直肠损伤,但均进行了一期缝合,无一例需要结肠造口术。平均住院时间为4天。25例(71%)患者的疾病局限于器官内。5例(14%)患者切缘阳性。17%的患者在1年后出现生化复发。76%的患者在1年后实现了控尿。
鉴于世界再次关注根治性会阴前列腺切除术,其学习曲线非常小,侵袭性最小且肿瘤控制良好,鉴于可用资源相对有限,印度次大陆的泌尿外科医生也应采用这一手术。