Suppr超能文献

退行性二尖瓣反流的后室间隔锚定腱索修复术可有效重塑和重新定位后瓣叶脱垂。

Posterior ventricular anchoring neochordal repair of degenerative mitral regurgitation efficiently remodels and repositions posterior leaflet prolapse.

机构信息

Department of Surgery, Division of Cardiovascular Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA.

出版信息

Eur J Cardiothorac Surg. 2013 Sep;44(3):485-9; discussion 489. doi: 10.1093/ejcts/ezt092. Epub 2013 Feb 28.

Abstract

OBJECTIVES

Mitral valve repair techniques for degenerative disease typically entail leaflet resection or neochordal construction, which may require extensive resection, leaflet detachment/reattachment, reliance on diseased native chords or precise neochordal measuring. Occasionally, impaired leaflet mobility, reduced coaptation surface and systolic anterior motion (SAM) may result. We describe a novel technique for addressing posterior leaflet prolapse/flail, which both simplifies repair and addresses these issues.

METHODS

Fifty-four patients (age 62 ± 11 years) with degenerative MR underwent this new repair, 36 of whom minimally-invasively. A CV5 Gore-Tex suture was placed into the posterior left ventricular myocardium underneath the prolapsing segment as an anchor. This suture was then used to imbricate a portion of the prolapsed segment into the ventricle, creating a smooth, broad, non-prolapsed coapting surface on a leaflet with preserved mobility, additional neochordal support and posteriorly positioned enough to preclude SAM.

RESULTS

Repair was successful in all patients. The mean MR grade was reduced from +3.8 to +0.1 with 50 of 54 patients having zero MR and 4 of the 54 having trace or mild MR. All patients had proper antero-posterior location of the coaptation line of a mean length of 10.2 mm, and preserved posterior leaflet mobility. No patients had SAM or mitral stenosis. All patients were discharged and are currently doing well.

CONCLUSION

This new technique facilitated efficient single-suture repair of the prolapsed posterior leaflet mitral regurgitation without the need for resection or sliding annuloplasty. It precluded the need for precise neochordal measurement and preserved the leaflet coaptation surface.

摘要

目的

退行性病变二尖瓣修复技术通常需要瓣叶切除术或人工腱索重建,这可能需要广泛的切除、瓣叶分离/再附着、依赖病变的固有腱索或精确的人工腱索测量。偶尔,会导致瓣叶活动受限、结合面积减小和收缩期前向运动(SAM)。我们描述了一种治疗后瓣叶脱垂/瓣叶游离的新方法,该方法既简化了修复,又解决了这些问题。

方法

54 例退行性二尖瓣关闭不全患者(年龄 62±11 岁)接受了这种新的修复,其中 36 例采用微创方法。在脱垂节段下方的左心室后侧壁心肌中放置一条 CV5 Gore-Tex 缝线作为锚点。然后,这条缝线被用来将脱垂节段的一部分嵌入心室,在保留瓣叶活动度的基础上,将脱垂段的一部分缝合到瓣叶上,形成一个平滑、宽阔、非脱垂的结合面,增加了人工腱索的支持,并将其置于足够的后位,以防止 SAM。

结果

所有患者的修复均成功。MR 分级从+3.8 级降至+0.1 级,54 例中有 50 例 MR 为零级,4 例为微量或轻度 MR。所有患者的前-后瓣叶结合线均位于适当位置,平均长度为 10.2mm,且后瓣叶活动度良好。无 SAM 或二尖瓣狭窄。所有患者均出院,目前情况良好。

结论

这种新技术通过单根缝线就能有效地修复脱垂的后瓣叶二尖瓣关闭不全,而无需进行瓣叶切除或滑动瓣环成形术。它避免了对精确的人工腱索测量的需求,并保留了瓣叶的结合面。

相似文献

8
Triangular resection versus neochordal replacement for posterior leaflet prolapse: a morphological assessment.
Interact Cardiovasc Thorac Surg. 2018 Jan 1;26(1):54-59. doi: 10.1093/icvts/ivx260.
9
Repair of posterior mitral valve prolapse with a novel leaflet plication clip in an animal model.新型瓣叶折叠夹在动物模型中修复二尖瓣后叶脱垂。
J Thorac Cardiovasc Surg. 2014 Feb;147(2):783-90; discussion 790-1. doi: 10.1016/j.jtcvs.2013.09.044. Epub 2013 Nov 8.

引用本文的文献

3
Neochords: How long, how many, too many?新索带:多长、多少、过多?
JTCVS Tech. 2023 Oct 28;22:59-64. doi: 10.1016/j.xjtc.2023.10.018. eCollection 2023 Dec.
8
Artificial papillary muscle device for off-pump transapical mitral valve repair.经皮体外循环二尖瓣修复的人工乳头肌装置。
J Thorac Cardiovasc Surg. 2022 Oct;164(4):e133-e141. doi: 10.1016/j.jtcvs.2020.11.105. Epub 2020 Nov 30.

本文引用的文献

2
Percutaneous repair or surgery for mitral regurgitation.经皮修复或手术治疗二尖瓣反流。
N Engl J Med. 2011 Apr 14;364(15):1395-406. doi: 10.1056/NEJMoa1009355. Epub 2011 Apr 4.
4
Repair of bileaflet prolapse in Barlow syndrome.巴洛综合征二瓣叶脱垂的修复。
Semin Thorac Cardiovasc Surg. 2010 Summer;22(2):174-8. doi: 10.1053/j.semtcvs.2010.09.006.
9
Minimally invasive valve surgery.微创瓣膜手术
Surg Clin North Am. 2009 Aug;89(4):923-49, x. doi: 10.1016/j.suc.2009.05.005.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验