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农村青少年失眠的一年病程和影响。

One-year course and effects of insomnia in rural Chinese adolescents.

机构信息

Department of Psychiatry, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong, China.

出版信息

Sleep. 2013 Mar 1;36(3):377-84. doi: 10.5665/sleep.2454.

Abstract

STUDY OBJECTIVES

We aimed to explore the incidence and persistence of insomnia, the associated risk factors, and the potential bidirectional association of insomnia with depression, anxiety, and sleepiness in rural Chinese adolescents.

DESIGN

School-based prospective study.

SETTING

Five high schools in rural China.

PARTICIPANTS

There were 2,787 adolescents studied.

INTERVENTIONS

N/A.

MEASURES AND RESULTS

Insomnia was defined as having a score of equal to or higher than nine in the Insomnia Severity Index as validated in Chinese adolescents. Depression, anxiety, and sleepiness were determined by the Beck Depression Inventory (BDI), Zung Self-Rating Anxiety Scale (SAS), and Epworth Sleepiness Scale (ESS), respectively. The incidence and persistence rates of insomnia were 16.0% and 41.0%, respectively. Multivariate analyses in logistic regression models revealed that new incidence of insomnia was significantly associated with age, living in a rural area, habitual daytime napping, high life events, anxiety, and depression at baseline (range adjusted odds ratio = 1.12-1.61), whereas the persistence of insomnia was positively associated with age, female sex, high life events, and depression at baseline (range adjusted odds ratio = 1.26-1.55) but negatively associated with living in a rural area (odds ratio = 0.59). Insomnia at baseline could predict new onsets of both depression (odds ratio = 1.45) and anxiety (odds ratio = 1.98) but not sleepiness at follow-up after adjustment for age, sex, and baseline symptoms. The results in cross-lagged analyses further supported these observations in the bidirectional associations of insomnia with depression, anxiety, and sleepiness.

CONCLUSIONS

Insomnia has considerable incidence and persistence rates in Chinese adolescents. We have identified several risk factors for the incidence and persistence of insomnia. There are bidirectional associations of insomnia with depression and anxiety but not sleepiness.

CITATION

Luo C; Zhang J; Pan J. One-year course and effects of insomnia in rural Chinese adolescents. SLEEP 2013;36(3):377-384.

摘要

研究目的

本研究旨在探讨农村青少年中失眠的发生率和持续性、相关危险因素,以及失眠与抑郁、焦虑和嗜睡之间潜在的双向关联。

设计

基于学校的前瞻性研究。

地点

中国农村的五所高中。

参与者

共有 2787 名青少年参与了研究。

干预措施

无。

测量和结果

失眠的定义为青少年中文版失眠严重程度指数(ISI)得分等于或高于 9 分。抑郁、焦虑和嗜睡分别由贝克抑郁量表(BDI)、zung 自评焦虑量表(SAS)和 Epworth 嗜睡量表(ESS)确定。失眠的发生率和持续性分别为 16.0%和 41.0%。多变量逻辑回归模型分析显示,新发失眠与年龄、农村居住、习惯性日间小睡、生活事件多、基线时的焦虑和抑郁显著相关(调整后比值比范围为 1.12-1.61),而失眠的持续性与年龄、女性、生活事件多和基线时的抑郁显著相关(调整后比值比范围为 1.26-1.55),但与农村居住呈负相关(比值比为 0.59)。基线时的失眠可预测抑郁(比值比为 1.45)和焦虑(比值比为 1.98)的新发发作,但在调整年龄、性别和基线症状后,与随访时的嗜睡无关。交叉滞后分析的结果进一步支持了这些关于失眠与抑郁、焦虑和嗜睡之间双向关联的观察结果。

结论

失眠在我国青少年中发生率和持续性都较高。我们已经确定了一些失眠发生率和持续性的危险因素。失眠与抑郁、焦虑存在双向关联,但与嗜睡无关。

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