用于实时成像卵巢组织的脉冲回波/光声经阴道探头的同配准。
Co-registered pulse-echo/photoacoustic transvaginal probe for real time imaging of ovarian tissue.
机构信息
Biomedical Engineering program and Electrical and Computer Engineering Department, University of Connecticut, Storrs CT 06269, USA.
出版信息
J Biophotonics. 2013 Jun;6(6-7):475-84. doi: 10.1002/jbio.201200163. Epub 2013 Mar 1.
Abstract
We present the design and construction of a prototype imaging probe capable of co-registered pulse-echo ultrasound and photoacoustic (optoacoustic) imaging in real time. The probe consists of 36 fibers of 200 micron core diameter each that are distributed around a commercial transvaginal ultrasound transducer, and housed in a protective shield. Its performance was demonstrated by two sets of experiments. The first set involved imaging of blood flowing through a tube mimicking a blood vessel, the second set involved imaging of human ovaries ex vivo. The results suggest that the system along with the probe has great potential for imaging and characterizing of ovarian tissue in vivo.
摘要
我们提出了一种实时共配准脉冲回波超声和光声（光声）成像的原型成像探头的设计和构建。该探头由 36 根 200 微米芯径的光纤组成，分布在一个商用经阴道超声换能器周围，并安装在一个保护罩内。通过两组实验验证了该探头的性能。第一组实验涉及模拟血管的管内血流成像，第二组实验涉及离体人卵巢成像。结果表明，该系统及其探头具有对体内卵巢组织进行成像和特征描述的巨大潜力。
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