Department of Veterinary Clinical Sciences, The Royal Veterinary College, UK.
Equine Vet J. 2013 Nov;45(6):666-70. doi: 10.1111/evj.12043. Epub 2013 Mar 4.
Clinical impression suggested that pony and miniature breeds (collectively referred to as ponies) presenting to a referral hospital for investigation of gastrointestinal disease had higher blood lactate concentrations on admission than large breed horses.
The study tested the hypothesis that ponies with gastrointestinal disease had higher blood lactate concentrations on admission than large breed horses with similar disease severity.
Retrospective case-control study.
Medical records from September 2006 to July 2011 were reviewed for ponies with a primary presenting complaint of gastrointestinal disease. Two larger breed horses with gastrointestinal disease were selected as controls for each case. Data collected included case details, historical and clinicopathological findings, diagnosis and outcome.
Information was collected on 50 ponies and 100 horses. Ponies had higher mean ± s.d. respiratory rates (27 ± 13 vs. 21 ± 13 beats/min; P = 0.01) and rectal temperatures (37.9 ± 0.6 vs. 37.4 ± 0.6°C; P = 0.006) and a longer median duration of clinical signs prior to presentation (10 h [1-72 h] vs. 6 h [1-120]; P<0.001). Median blood lactate concentrations on admission were higher in ponies than in horses (2.8 mmol/l [0.7-18.0] vs. 1.6 mmol/l [0.4-8.1]; P = 0.001). All other parameters relating to colic severity were not significantly different between groups, although more horses underwent exploratory laparotomy (19/50 ponies and 55/100 horses; P = 0.05). Median blood lactate concentrations in ponies with large intestinal disease, nonstrangulating lesions, undergoing medical treatment and surviving ponies were significantly higher than in horses in the same category. In contrast to horses, no differences in blood lactate concentrations exist between ponies with medical vs. surgical treatment, strangulating and nonstrangulating lesions and surviving and nonsurviving ponies.
Ponies might present with higher blood lactate concentrations than horses and might falsely be suspected of having a surgical lesion or a poorer prognosis if veterinarians are not aware of breed differences.
临床印象表明，就诊于转诊医院进行胃肠道疾病检查的小型马和迷你马（统称小马）入院时的血乳酸浓度高于大型马。
该研究检验了以下假设，即患有胃肠道疾病的小马的血乳酸浓度高于患有类似严重程度疾病的大型马。
回顾性病例对照研究。
对 2006 年 9 月至 2011 年 7 月期间因胃肠道疾病主要就诊的小马的病历进行了回顾。为每个病例选择了 2 匹具有类似胃肠道疾病的较大体型马作为对照。收集的数据包括病例详细信息、历史和临床病理发现、诊断和结果。
共收集了 50 匹小马和 100 匹马的信息。小马的平均呼吸频率（27 ± 13 次/分钟比 21 ± 13 次/分钟；P = 0.01）和直肠温度（37.9 ± 0.6°C 比 37.4 ± 0.6°C；P = 0.006）较高，在就诊前的临床症状持续时间中位数较长（10 小时[1-72 小时]比 6 小时[1-120 小时]；P<0.001）。入院时小马的血乳酸浓度中位数高于马（2.8 mmol/L[0.7-18.0]比 1.6 mmol/L[0.4-8.1]；P = 0.001）。虽然更多的马接受了剖腹探查术（19/50 匹小马和 55/100 匹马；P = 0.05），但与绞痛严重程度相关的其他参数在两组之间没有显著差异。患有大肠疾病、非绞窄性病变、接受药物治疗和存活的小马的血乳酸浓度中位数明显高于同组的马。与马不同，接受药物治疗与手术治疗、绞窄性与非绞窄性病变以及存活与非存活小马之间的血乳酸浓度没有差异。
兽医如果不了解品种差异，小马可能会表现出比马更高的血乳酸浓度，并且如果兽医不了解品种差异，可能会错误地怀疑小马存在手术病变或预后不良。
