Service d'ORL et Chirurgie Cervico-Faciale, Centre Hospitalier Universitaire (CHU) La Timone, Assistance Publique-Hôpitaux de Marseille (AP-HM)/Aix-Marseille Université, 264, rue Saint Pierre, 13385, Marseille Cedex 05, France.
Dysphagia. 2013 Sep;28(3):435-45. doi: 10.1007/s00455-013-9457-x. Epub 2013 Feb 28.
The aim of this study was to obtain a quantitative anatomical description of the hyoid bone using modern 3D reconstruction tools and to discuss potential applications of the knowledge in clinical practice. The study was conducted on 88 intact hyoid bones taken from cadavers during forensic autopsies (group 1) and on 92 bones from CT scan images of living adult subjects (group 2). Three-dimensional reconstructions were created from CT scan images using Amira 5.3.3® software. An anatomical and anthropological study of hyoid bones was carried out using metric and morphological analyses. Groups 1 and 2 were compared to evaluate the influence of muscle traction on hyoid bone shape. Characteristics of the hyoid bone were highly heterogeneous and were closely linked with the sex, height, and weight of the individuals. Length and width were significantly greater in men than in women (39.08 vs. 32.50 mm, p = 0.033 and 42.29 vs. 38.61 mm, p = 0.003), whereas the angle between the greater horns was larger in females (44.09 vs. 38.78, p = 0.007). There was a significant positive correlation between the height (Pearson coefficient correlation r = 0.533, p = 0.01) and weight (r = 0.497, p = 0.01) of subjects and the length of the hyoid bone. Significant metric differences were shown between group 1 and group 2. This very reproducible methodology is important because it may lead to clinical studies in, e.g., head and neck cancer or sleep apnea. Such studies are ongoing in our research program.
本研究旨在利用现代 3D 重建工具对舌骨进行定量解剖描述，并探讨该知识在临床实践中的潜在应用。该研究在 88 例尸检中获得的完整舌骨（第 1 组）和 92 例成人活体 CT 扫描图像中的舌骨（第 2 组）上进行。使用 Amira 5.3.3®软件对 CT 扫描图像进行三维重建。使用计量和形态学分析对舌骨进行解剖学和人类学研究。对第 1 组和第 2 组进行比较，以评估肌肉牵引对舌骨形状的影响。舌骨的特征高度异质，与个体的性别、身高和体重密切相关。男性的长度和宽度明显大于女性（39.08 与 32.50mm，p=0.033 和 42.29 与 38.61mm，p=0.003），而女性的大角之间的角度更大（44.09 与 38.78，p=0.007）。受试者的身高（Pearson 系数相关 r=0.533，p=0.01）和体重（r=0.497，p=0.01）与舌骨长度呈显著正相关。第 1 组和第 2 组之间显示出显著的度量差异。这种非常可重复的方法很重要，因为它可能导致头颈部癌症或睡眠呼吸暂停等临床研究。此类研究正在我们的研究计划中进行。
