Institute of Sports Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany,
Psychiatr Q. 2013 Dec;84(4):417-27. doi: 10.1007/s11126-013-9256-4.
The aim of this study was to resolve the relationship between physical capacity (PC) and quality of life (Qol) in schizophrenic patients and healthy controls. 31 patients (PG: 18 male, 13 female) and a control group (CG) of 50 healthy subjects (15 male, 35 female) were involved. PC was assessed as peak oxygen uptake [VO2peak, (ml (min kgKG)(-1))] and power output expressed as watts per kilogram (W kg(-1)). Qol was assessed using the SF-36 questionnaire. Patients with schizophrenia showed reduced VO2peak (male: PG 29 ± 5 vs. CG 44 ± 10; female: PG 21 ± 4 vs. CG 30 ± 8) and power output (male: PG 2.04 ± 0.47 vs. CG 3.43 ± 0.70; female PG 1.40 ± 0.28 vs. CG 2.43 ± 0.52). Scales of the SF-36 questionnaire were lower in the PG. While in the CG correlations were found between PC and several subscales of Qol, this was not the case in the PG. The restricted PC seen in the PG showed no relation to their subjectively assessed worsened Qol, which would indicate that schizophrenic patients evaluate limitations arising from this differently than healthy control subjects.
本研究旨在解决精神分裂症患者与健康对照组之间的身体能力 (PC) 和生活质量 (Qol) 之间的关系。共纳入 31 名患者 (PG: 18 名男性，13 名女性) 和 50 名健康对照组 (CG: 15 名男性，35 名女性)。PC 评估为峰值摄氧量 [VO2peak，(ml (min kgKG)(-1))] 和以每公斤瓦特表示的功率输出 (W kg(-1))。Qol 采用 SF-36 问卷进行评估。精神分裂症患者的 VO2peak 降低 (男性: PG 29 ± 5 与 CG 44 ± 10; 女性: PG 21 ± 4 与 CG 30 ± 8) 和功率输出 (男性: PG 2.04 ± 0.47 与 CG 3.43 ± 0.70; 女性 PG 1.40 ± 0.28 与 CG 2.43 ± 0.52)。PG 的 SF-36 问卷各量表评分较低。而在 CG 中，PC 与 Qol 的几个亚量表之间存在相关性，但在 PG 中则没有。PG 中观察到的受限 PC 与其主观评估的 Qol 恶化没有关系，这表明精神分裂症患者对由此产生的限制的评估与健康对照组不同。
