Choi Yoonhee, Cho Kwanghyun, Yoon Soonyoung, Lee Hyungmin, Choi Younghwan
Department of Emergency Medicine, Eulji University, Seoul, South Korea.
Am J Emerg Med. 2008 Sep;26(7):836.e3-4. doi: 10.1016/j.ajem.2007.12.016.
Paraquat intoxication is a fatal problem. Most paraquat intoxications happen through oral administration. We report a case of death after intravenous paraquat injection. There is little clinical data on parenteral paraquat exposure, and we describe this case and fatal progression. Toxic symptoms and severe organ function impairment developed soon after injection. Treatment with repeated activated charcoal hemoperfusion with pulse steroids, cyclophosphamide, and antioxidants was attempted. The patient died from multiple organ failure 3 days after intoxication. This case indicates that paraquat intoxication via intravenous injection, even in very small amounts, has an extremely poor prognosis.
百草枯中毒是一个致命问题。大多数百草枯中毒是通过口服发生的。我们报告一例静脉注射百草枯后的死亡病例。关于胃肠外接触百草枯的临床数据很少，我们描述了该病例及其致命进展。注射后很快出现中毒症状和严重的器官功能损害。尝试采用重复活性炭血液灌流联合脉冲类固醇、环磷酰胺和抗氧化剂进行治疗。患者在中毒3天后死于多器官功能衰竭。该病例表明，即使极少量的静脉注射百草枯中毒预后也极差。
