Kulikova E I, Kriuchkova D M, Severiukhin Iu S, Gaevskiĭ V N, Ivanov A A
Aviakosm Ekolog Med. 2012 Nov-Dec;46(6):45-50.
Experiments were performed with outbreed mice CD-I and hybrid mice (CBA' C57BI)F1. Seven to 21 days before irradiation, the mice had continuously consumed light-isotope water (35 ppm) produced by rectification w/o secondary treatment. Dose of single gamma-irradiation ranged from 4 to 8.5 Gy. The radiomodifying effects included statistically reliable reductions in survivability and life span, loss of body mass, and decreases in marrow myelokaryocytes and peripheral leukocytes. In 8-9 days after irradiation, spleen mass in the experimental mice was found enlarged as compared with the controls.
实验使用远交系小鼠CD-I和杂交小鼠（CBA×C57BI）F1进行。在照射前7至21天，小鼠持续饮用未经二次处理通过精馏产生的轻同位素水（35 ppm）。单次γ射线照射剂量范围为4至8.5 Gy。辐射修饰效应包括在生存率和寿命方面具有统计学意义的可靠降低、体重减轻以及骨髓髓细胞和外周白细胞减少。照射后8至9天，发现实验小鼠的脾脏重量比对照组增大。
