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[轻同位素水作为急性放射病的治疗剂]

[Light-isotope water as a therapeutic agent for acute radiation disease].

作者信息

Ivanov A A, Ushakov I B, Kulikova E I, Kriuchkova D M, Severiukhin Iu S, Vorozhtsova S V, Abrosimova A N, Gaevskiĭ V A, Siniak Iu E, Grigor'ev A I

出版信息

Aviakosm Ekolog Med. 2013 Sep-Oct;47(5):40-4.

PMID:24490286
Abstract

Eighty outbred CD-I male and female mice (initial body mass of 31-34 g) and 40 male Wistar rats (initial body mass of 280-360 g) were randomly distributed into the experimental and control groups by sex and body mass. According to the results of experiments, consumption of rectified light-isotope water over 30 days immediately after irradiation by gamma-quanta 60Co at 5 Gy and 6.5 Gy can increase survivability rate significantly, accelerate hemopoiesis recovery and prevent body mass loss in irradiated animals. Therefore, light-isotope water can be considered as an effective agent for treatment of the bone marrow syndrome.

摘要

80只远交群CD-I雄性和雌性小鼠(初始体重31 - 34克)以及40只雄性Wistar大鼠(初始体重280 - 360克)按性别和体重随机分为实验组和对照组。根据实验结果,在接受5 Gy和6.5 Gy的60Coγ射线照射后立即饮用精馏轻同位素水30天,可显著提高受照动物的存活率,加速造血恢复并防止体重减轻。因此,轻同位素水可被视为治疗骨髓综合征的有效药剂。

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