脑信号瞬息变化：人类大脑绘图的下一个前沿领域？
Moment-to-moment brain signal variability: a next frontier in human brain mapping?
机构信息
Max Planck Society-University College London Initiative: Computational Psychiatry and Aging Research (ICPAR); Center for Lifespan Psychology, Max Planck Institute for Human Development, Lentzeallee 94, 14195 Berlin, Germany.
出版信息
Neurosci Biobehav Rev. 2013 May;37(4):610-24. doi: 10.1016/j.neubiorev.2013.02.015. Epub 2013 Mar 1.
Abstract
Neuroscientists have long observed that brain activity is naturally variable from moment-to-moment, but neuroimaging research has largely ignored the potential importance of this phenomenon. An emerging research focus on within-person brain signal variability is providing novel insights, and offering highly predictive, complementary, and even orthogonal views of brain function in relation to human lifespan development, cognitive performance, and various clinical conditions. As a result, brain signal variability is evolving as a bona fide signal of interest, and should no longer be dismissed as meaningless noise when mapping the human brain.
摘要
神经科学家早就观察到，大脑活动在时刻之间是自然变化的，但神经影像学研究在很大程度上忽略了这种现象的潜在重要性。目前，人们越来越关注个体内部的大脑信号变化，这为我们提供了新的见解，使我们能够从高度预测性、互补性甚至正交的角度来观察大脑功能与人类寿命发展、认知表现和各种临床状况的关系。因此，大脑信号变化正在成为一种可靠的研究信号，在绘制人类大脑图谱时，它不应该再被视为无意义的噪声而被忽略。
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