Division of Global HIV/AIDS, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
PLoS One. 2013;8(2):e57215. doi: 10.1371/journal.pone.0057215. Epub 2013 Feb 25.
HIV care and treatment settings provide an opportunity to reach people living with HIV/AIDS (PLHIV) with prevention messages and services. Population-based surveys in sub-Saharan Africa have identified HIV risk behaviors among PLHIV, yet data are limited regarding HIV risk behaviors of PLHIV in clinical care. This paper describes the baseline sociodemographic, HIV transmission risk behaviors, and clinical data of a study evaluating an HIV prevention intervention package for HIV care and treatment clinics in Africa. The study was a longitudinal group-randomized trial in 9 intervention clinics and 9 comparison clinics in Kenya, Namibia, and Tanzania (N = 3538). Baseline participants were mostly female, married, had less than a primary education, and were relatively recently diagnosed with HIV. Fifty-two percent of participants had a partner of negative or unknown status, 24% were not using condoms consistently, and 11% reported STI symptoms in the last 6 months. There were differences in demographic and HIV transmission risk variables by country, indicating the need to consider local context in designing studies and using caution when generalizing findings across African countries. Baseline data from this study indicate that participants were often engaging in HIV transmission risk behaviors, which supports the need for prevention with PLHIV (PwP).
ClinicalTrials.gov NCT01256463.
艾滋病毒护理和治疗环境为向艾滋病毒/艾滋病感染者（PLHIV）提供预防信息和服务提供了机会。撒哈拉以南非洲的基于人群的调查已经确定了 PLHIV 中的艾滋病毒风险行为，但关于临床护理中 PLHIV 的艾滋病毒风险行为的数据有限。本文描述了评估在非洲艾滋病毒护理和治疗诊所实施艾滋病毒预防干预包的研究的基线社会人口统计学，艾滋病毒传播风险行为和临床数据。该研究是在肯尼亚，纳米比亚和坦桑尼亚的 9 个干预诊所和 9 个对照诊所中进行的一项纵向群组随机试验（N = 3538）。基线参与者主要是女性，已婚，受教育程度低于小学，并且最近被诊断出患有艾滋病毒。52％的参与者的伴侣呈阴性或未知状态，24％的人没有坚持使用避孕套，11％的人在过去 6 个月中有性病症状。按国家划分，人口统计学和艾滋病毒传播风险变量存在差异，这表明在设计研究时需要考虑当地情况，并在将研究结果推广到非洲国家时要谨慎。该研究的基线数据表明，参与者经常从事艾滋病毒传播风险行为，这支持了需要对 PLHIV（PwP）进行预防。
ClinicalTrials.gov NCT01256463。
