用来自大脑的制剂、5-甲基四氢叶酸和色胺形成色氨酸。
Tryptoline formation by a preparation from brain with 5-methyltetrahydrofolic acid and tryptamine.
作者信息
Wyatt R J, Erdelyi E, DoAmaral J R, Elliott G R, Renson J, Barchas J D
出版信息
Science. 1975 Mar 7;187(4179):853-5. doi: 10.1126/science.234627.
PMID:234627
Abstract
An enzymatic preparation from human brain converts tryptamine to tryptoline (9H-1,2,3,4-tetrahydropyrido[3,4-b]indole) in the presence of 5-methyltetrahydrofolic acid. Similarly, N-methyltryptamine and 5-hydroxytryptamine yield 1-methyltryptoline and 5-hydroxytryptoline, respectively. Neither in vitro nor in vivo formation of these compounds by human tissues has been described.
摘要
人脑的一种酶制剂在5-甲基四氢叶酸存在的情况下可将色胺转化为色醇（9H-1,2,3,4-四氢吡啶并[3,4-b]吲哚）。同样，N-甲基色胺和5-羟色胺分别生成1-甲基色醇和5-羟色醇。人体组织在体外或体内形成这些化合物的情况均未见报道。
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