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香港受多环芳烃污染土壤的癌症风险评估。

Cancer risk assessments of Hong Kong soils contaminated by polycyclic aromatic hydrocarbons.

机构信息

School of Environmental and Resource Sciences, Zhejiang Agriculture and Forestry University, Lin'an, Zhejiang 311300, PR China; State Key Laboratory in Marine Pollution - Croucher Institute for Environmental Sciences, Hong Kong Baptist University and City University of Hong Kong, Hong Kong SAR, PR China.

出版信息

J Hazard Mater. 2013 Oct 15;261:770-6. doi: 10.1016/j.jhazmat.2012.11.067. Epub 2013 Feb 1.

Abstract

The aim of this study was to evaluate soils from 12 different land use types on human cancer risks, with the main focus being on human cancer risks related to polycyclic aromatic hydrocarbons (PAHs). Fifty-five locations were selected to represent 12 different types of land use (electronic waste dismantling workshop (EW (DW)); open burning site (OBS); car dismantling workshop (CDW) etc.). The total concentrations of 16 PAHs in terms of total burden and their bioaccessibility were analysed using GC/MS. The PAHs concentrations were subsequently used to establish cancer risks in humans via three exposure pathways, namely, accident ingestion of soil, dermal contact soil and inhalation of soil particles. When the 95th centile values of total PAH concentrations were used to derive ingestion and dermal cancer risk probabilities on humans, the CDW land use type indicated a moderate potential for cancerous development (244 × 10(-6) and 209 × 10(-6), respectively). Bioaccessible PAHs content in soil samples from CDW (3.60 × 10(-6)) were also classified as low cancer risk. CDW soil possessed a higher carcinogenic risk based on PAH concentrations. Bioremediation is recommended to treat the contaminated soil.

摘要

本研究旨在评估 12 种不同土地利用类型的土壤对人类癌症风险的影响,重点关注与多环芳烃(PAHs)相关的人类癌症风险。选择了 55 个地点来代表 12 种不同类型的土地利用(电子废物拆解车间(EW(DW));露天焚烧场(OBS);汽车拆解车间(CDW)等)。使用 GC/MS 分析了总浓度为 16 种 PAHs 的总负担及其生物可利用性。随后,使用 PAHs 浓度通过三种暴露途径(意外摄入土壤、皮肤接触土壤和吸入土壤颗粒)来确定人类癌症风险。当使用总 PAH 浓度的第 95 百分位值来推导人类的摄入和皮肤癌症风险概率时,CDW 土地利用类型表明存在中度癌症发展潜力(分别为 244×10(-6)和 209×10(-6))。CDW 土壤中可生物利用的 PAHs 含量(3.60×10(-6))也被归类为低癌症风险。基于 PAH 浓度,CDW 土壤具有更高的致癌风险。建议采用生物修复来处理受污染的土壤。

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