阿考他丁A的简洁全合成
Concise total synthesis of acortatarin A.
作者信息
Teranishi Takaaki, Kageyama Masayuki, Kuwahara Shigefumi
机构信息
Laboratory of Applied Bioorganic Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan.
出版信息
Biosci Biotechnol Biochem. 2013;77(3):676-8. doi: 10.1271/bbb.120862. Epub 2013 Mar 7.
PMID:23470747
Abstract
The spirocyclic pyrrole alkaloid, acortatarin A, which had been isolated from a Chinese medicinal plant, was synthesized from a known olefinic compound by a concise six-step sequence involving N-alkylation of a pyrrole derivative with an α-bromo ketone intermediate as the key step.
摘要
从一种中国药用植物中分离得到的螺环吡咯生物碱阿考他丁A，是由一种已知的烯烃化合物通过一个简洁的六步序列合成的，该序列以吡咯衍生物与α-溴代酮中间体的N-烷基化反应为关键步骤。
Zotero 插件