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正常受试者在寒冷环境温度下运动后的肺功能。

Pulmonary function in normal subjects following exercise at cold ambient temperatures.

作者信息

Chapman K R, Allen L J, Romet T T

机构信息

Asthma Centre, Toronto Hospital, Ontario, Canada.

出版信息

Eur J Appl Physiol Occup Physiol. 1990;60(3):228-32. doi: 10.1007/BF00839164.

Abstract

We measured pulmonary function in 12 healthy volunteers before and at 5-min intervals for 30 min following treadmill exercise of 30 min duration performed under control (20 degrees C) and cold (-11 degrees C) ambient temperatures. Post-run changes in forced vital capacity (FVC), residual volume (RV) and peak expiratory flow rate were similar between the two temperature conditions. FVC decreased slightly but significantly 5 min post-run (-0.25 +/- 0.20 l and -0.21 +/- 0.20 l, for control and cold conditions respectively) and returned to baseline by 30 min. RV increased significantly post-exercise (+0.07 +/- 0.09 l and +0.14 +/- 0.1 l, control and cold respectively) and remained elevated for 30 min. Forced expired volume in 1 s was not significantly different following either run. Post-exercise, maximum mid-expiratory flow rate and flows at 50% and 25% of vital capacity were not significantly different between warm and cold conditions. These data suggest that changes in lung volumes following exercise under cold ambient conditions are similar to changes seen following warm exercise of similar duration. In non-asthmatics, moderate exertion under cold ambient conditions does not appear to cause clinically significant decreases in expiratory flow rates as compared to similar exertion under warm conditions.

摘要

我们在12名健康志愿者身上进行了如下实验:在20摄氏度(常温)和零下11摄氏度(低温)的环境温度下,让他们在跑步机上进行30分钟的运动,运动前及运动后每隔5分钟测量一次肺功能,共测量30分钟。在两种温度条件下,运动后用力肺活量(FVC)、残气量(RV)和呼气峰值流速的变化相似。运动后5分钟,FVC略有下降但具有统计学意义(常温组下降0.25±0.20升,低温组下降0.21±0.20升),到30分钟时恢复至基线水平。运动后RV显著增加(常温组增加0.07±0.09升,低温组增加0.14±0.1升),并在30分钟内一直保持升高。两种运动后1秒用力呼气量均无显著差异。运动后,常温与低温条件下的最大呼气中期流速以及肺活量50%和25%时的流速均无显著差异。这些数据表明,在低温环境下运动后肺容量的变化与在类似时长的常温运动后观察到的变化相似。在非哮喘患者中,与常温条件下的类似运动相比,低温环境下的适度运动似乎不会导致呼气流量出现具有临床意义的显著下降。

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