Department of Chemical and Biomolecular Engineering, Pusan National University, San 30, Jangjeon-dong, Geumjeong-gu, Busan 609-735, Republic of Korea.
Biotechnol Adv. 2013 Nov;31(6):945-61. doi: 10.1016/j.biotechadv.2013.02.008. Epub 2013 Mar 6.
3-Hydroxypropionic acid (3-HP) is a valuable platform chemical that can be produced biologically from glucose or glycerol. This review article provides an overview and the current status of microbial 3-HP production. The constraints of microbial 3-HP production and possible solutions are also described. Finally, future prospects of biological 3-HP production are discussed.
3-羟基丙酸(3-HP)是一种有价值的平台化学品,可从葡萄糖或甘油生物合成。本文综述了微生物 3-HP 生产的概况和现状。还描述了微生物 3-HP 生产的限制因素和可能的解决方案。最后,讨论了生物 3-HP 生产的未来前景。