一名免疫功能正常的患者因原发性血小板增多症长期使用乙胺嘧啶后发生皮肤浆母细胞淋巴瘤：病例报告及文献复习
Cutaneous plasmablastic lymphoma in an immunocompetent patient with long-term pyrimethamine use for essential thrombocythemia: a case report and literature review.
作者信息
Tiong Ing Soo, Strauss Magreet, Lau Michael B Y, Chiruka Shingirai
机构信息
Southern Blood and Cancer Service, Dunedin Hospital, Private Bag 1921, Dunedin 9054, New Zealand.
出版信息
Case Rep Hematol. 2013;2013:541783. doi: 10.1155/2013/541783. Epub 2013 Feb 6.
Abstract
We report a case of Epstein-Barr-virus-(EBV-) positive primary cutaneous plasmablastic lymphoma in a human-immunodeficiency-virus-(HIV-) negative, immunocompetent 62-year-old female patient. We postulate that her lymphoma development is due to the longstanding use of pyrimethamine for essential thrombocythemia. This has never been described in the literature.
摘要
我们报告了一例爱泼斯坦-巴尔病毒（EBV）阳性的原发性皮肤浆母细胞淋巴瘤病例，患者为一名62岁免疫功能正常的女性，人类免疫缺陷病毒（HIV）阴性。我们推测她的淋巴瘤发展是由于长期使用乙胺嘧啶治疗原发性血小板增多症所致。这在文献中从未有过描述。
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