Smith Laramie R, Amico K Rivet, Shuper Paul A, Christie Sarah, Fisher William A, Cornman Deborah H, Doshi Monika, MacDonald Susan, Pillay Sandy, Fisher Jeffrey D
a Center for Health Intervention, and Prevention , University of Connecticut , Storrs, Connecticut , CT , USA.
AIDS Care. 2013;25(12):1485-90. doi: 10.1080/09540121.2013.775398. Epub 2013 Mar 11.
Little is known regarding factors implicated in early engagement and retention in HIV care among individuals not yet eligible for antiretroviral therapy (pre-ART) in sub-Saharan Africa. Identifying such factors is critical for supporting retention in pre-ART clinical care to ensure timely ART initiation and optimize long-term health outcomes. We assessed patients' pre-ART HIV care-related information, motivation, and behavioral skills among newly diagnosed ART-ineligible patients, initiating care in KwaZulu-Natal, South Africa. The survey was interviewer-administered to eligible patients, who were aged 18 years or older, newly entering care (diagnosed within the last six-months), and ineligible for ART (CD4 count > 200 cells/mm(3)) in one of four primary care clinical sites. Self-reported information, motivation, and behavioral skills specific to retention in pre-ART HIV-care were characterized by categorizing responses into those reflecting potential strengths and those reflective of potential deficits. Information, motivation, and behavioral skills deficits sufficiently prevalent in the overall sample (i.e.,≥30% prevalent) were identified as areas in need of specific attention through intervention efforts adapted to the clinic level. Gender-based differences were also evaluated. A total of 288 patients (75% female) completed structured interviews. Across the sample, eight information, eight motivation, and eight behavioral skills deficit areas were identified as sufficiently prevalent to warrant specific targeted attention. Gender differences did not emerge. The deficits in pre-ART HIV care-related information, motivation, and behavioral skills that were identified suggest that efforts to improve accurate information on immune function and HIV disease are needed, as is accurate information regarding HIV treatment and transmission risk prior to ART initiation. Additional efforts to facilitate the development of social support, including positive interactions with clinic staff and decreasing community-level stigma and to decrease structural and resource-depleting demands of HIV care may be particularly valuable to facilitate retention in pre-ART HIV care.
在撒哈拉以南非洲地区,对于尚未符合抗逆转录病毒治疗条件(治疗前)的个体,参与并坚持接受艾滋病病毒治疗的相关因素鲜为人知。识别这些因素对于支持他们坚持治疗前的临床护理、确保及时开始抗逆转录病毒治疗以及优化长期健康结果至关重要。我们评估了南非夸祖鲁 - 纳塔尔省新诊断为不符合抗逆转录病毒治疗条件且开始接受护理的患者在治疗前与艾滋病病毒护理相关的信息、动机和行为技能。该调查由访员对符合条件的患者进行,这些患者年龄在18岁及以上,新进入护理(在过去六个月内确诊),并且在四个初级保健临床地点之一不符合抗逆转录病毒治疗条件(CD4细胞计数>200个细胞/mm³)。通过将对治疗前艾滋病病毒护理坚持情况的自我报告信息、动机和行为技能的回答分为反映潜在优势和潜在不足的两类来进行特征描述。在整个样本中普遍存在(即≥30%)的信息、动机和行为技能不足被确定为需要通过适合诊所层面的干预措施予以特别关注的领域。还评估了基于性别的差异。共有288名患者(75%为女性)完成了结构化访谈。在整个样本中,八个信息、八个动机和八个行为技能不足领域被确定为普遍存在,足以值得进行特定的针对性关注。未发现性别差异。所确定的治疗前艾滋病病毒护理相关信息、动机和行为技能方面的不足表明,需要努力改善关于免疫功能和艾滋病病毒疾病的准确信息,以及在开始抗逆转录病毒治疗之前关于艾滋病病毒治疗和传播风险的准确信息。为促进社会支持的发展做出额外努力,包括与诊所工作人员进行积极互动、减少社区层面的耻辱感,以及减少艾滋病病毒护理的结构和资源消耗需求,对于促进治疗前艾滋病病毒护理的坚持可能特别有价值。