消毒剂对血液透析中念珠菌属近平滑假丝酵母菌和严格意义上的中间假丝酵母菌生物膜的有效性。
Effectiveness of disinfectants used in hemodialysis against both Candida orthopsilosis and C. parapsilosis sensu stricto biofilms.
机构信息
Departamento de Análises Clínicas, Faculdade de Ciências Farmacêuticas, Univ Estadual Paulista-UNESP, Araraquara, São Paulo, Brazil.
出版信息
Antimicrob Agents Chemother. 2013 May;57(5):2417-21. doi: 10.1128/AAC.01308-12. Epub 2013 Mar 11.
Abstract
Biofilms have been observed in the fluid pathways of hemodialysis machines. The impacts of four biocides used for the disinfection of hemodialysis systems were tested against Candida parapsilosis sensu stricto and Candida orthopsilosis biofilms generated by isolates obtained from a hydraulic circuit that were collected in a hemodialysis unit. Acetic acid was shown to be the most effective agent against Candida biofilms. Strategies for effective disinfection procedures used for hemodialysis systems should also seek to kill and inhibit biofilms.
摘要
生物膜已在血液透析机的流体通道中被观察到。测试了四种用于血液透析系统消毒的杀生物剂对源自液压回路的分离株所产生的近平滑假丝酵母和近平滑假丝酵母生物膜的影响，这些分离株是在血液透析病房中收集的。乙酸被证明是对抗假丝酵母生物膜最有效的药剂。用于血液透析系统的有效消毒程序的策略也应寻求杀死和抑制生物膜。
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