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使用偏振多光谱皮肤镜对皮肤病变进行光谱形态分析。

Spectral morphological analysis of skin lesions with a polarization multispectral dermoscope.

作者信息

Kapsokalyvas Dimitrios, Bruscino Nicola, Alfieri Domenico, de Giorgi Vincenzo, Cannarozzo Giovanni, Cicchi Riccardo, Massi Daniela, Pimpinelli Nicola, Pavone Francesco S

机构信息

European Laboratory for Non-linear Spectroscopy (LENS), Univ. of Florence, 50019 Sesto-Fiorentino, Italy.

出版信息

Opt Express. 2013 Feb 25;21(4):4826-40. doi: 10.1364/OE.21.004826.

Abstract

Dermoscopy is the conventional technique used for the clinical inspection of human skin lesions. However, the identification of diagnostically relevant morphologies can become a complex task. We report on the development of a polarization multispectral dermoscope for the in vivo imaging of skin lesions. Linearly polarized illumination at three distinct spectral regions (470, 530 and 625 nm), is performed by high luminance LEDs. Processing of the acquired images, by means of spectral and polarization filtering, produces new contrast images, each one specific for melanin absorption, hemoglobin absorption, and single scattering. Analysis of such images could facilitate the identification of pathological morphologies.

摘要

皮肤镜检查是用于临床检查人类皮肤病变的传统技术。然而,识别具有诊断意义的形态可能会成为一项复杂的任务。我们报告了一种用于皮肤病变活体成像的偏振多光谱皮肤镜的开发情况。通过高亮度发光二极管在三个不同光谱区域(470、530和625纳米)进行线性偏振照明。通过光谱和偏振滤波对采集到的图像进行处理,可以生成新的对比图像,每一幅图像都针对黑色素吸收、血红蛋白吸收和单次散射具有特异性。对这些图像的分析有助于识别病理形态。

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