Zhang Su-Jing, Zhuo Xian-Yi, Ma Dong
School of Pharmacy, Medical College of Soochow University, Suzhou 215123, China.
Fa Yi Xue Za Zhi. 2012 Dec;28(6):456-60, 463.
Inductively coupled plasma-mass spectrometry (ICP-MS) is the most common technique for elements analysis at present. ICP-MS with high sensitivity and wide linear range can be applied to multi-elements analysis in blood and urine. This paper reviews the common means of sample pretreatment (direct dilution method and wet digestion method), the method for correction of mass spectral interference and non-interference, the main influence factors of analysis results, and provides an outlook of the application of ICP-MS in forensic toxicological analysis.
电感耦合等离子体质谱法（ICP-MS）是目前元素分析中最常用的技术。具有高灵敏度和宽线性范围的ICP-MS可应用于血液和尿液中的多元素分析。本文综述了常见的样品预处理方法（直接稀释法和湿式消解法）、质谱干扰校正方法和无干扰方法、分析结果的主要影响因素，并对ICP-MS在法医毒理学分析中的应用前景进行了展望。
