Department of Plant Pathology & Microbiology, University of California, Riverside, CA, USA.
Mol Plant Microbe Interact. 2013 Jun;26(6):617-25. doi: 10.1094/MPMI-10-12-0255-IA.
Small RNAs regulate a multitude of cellular processes, including development, stress responses, metabolism, and maintenance of genome integrity, in a sequence-specific manner. Accumulating evidence reveals that host endogenous small RNAs and small RNA pathway components play important roles in plant immune responses against various pathogens, including bacteria, fungi, oomycetes, and viruses. Small-RNA-mediated defense responses are regulated through diverse pathways and the components of these pathways, including Dicer-like proteins, RNA-dependent RNA polymerases, Argonaute proteins, and RNA polymerase IV and V, exhibit functional specificities as well as redundancy. In this review, we summarize the recent insights revealed mainly through the examination of two model plants, Arabidopsis and rice, with a primary focus on our emerging understanding of how these small RNA pathway components contribute to plant immunity.
小 RNA 以序列特异性方式调节多种细胞过程，包括发育、应激反应、代谢和基因组完整性的维持。越来越多的证据表明，宿主内源性小 RNA 和小 RNA 通路成分在植物对各种病原体（包括细菌、真菌、卵菌和病毒）的免疫反应中发挥重要作用。小 RNA 介导的防御反应通过多种途径进行调节，这些途径的成分，包括 Dicer-like 蛋白、RNA 依赖性 RNA 聚合酶、Argonaute 蛋白以及 RNA 聚合酶 IV 和 V，表现出功能特异性和冗余性。在这篇综述中，我们主要通过对两种模式植物拟南芥和水稻的研究，总结了最近的研究进展，重点介绍了我们对这些小 RNA 通路成分如何参与植物免疫的理解的最新进展。
