Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, SE-205 02 Malmö, Sweden.
Curr Diab Rep. 2013 Jun;13(3):372-80. doi: 10.1007/s11892-013-0373-0.
The cost of treating cardiovascular disease (CVD) and diabetes is enormous and is set to rise in the coming years. Physical inactivity and sedentary behaviors are major risk factors for these diseases and are estimated to account for several million global deaths annually. Lifestyle interventions, particularly those aimed at enhancing physical activity levels, have a substantial favorable impact on diabetes progression in people at high risk of the disease. Although observational studies and small intervention studies suggest that physical activity might also prevent CVD in people with diabetes, this is not supported by the results of larger randomized controlled trials of lifestyle intervention. The purpose of this review is to provide an overview of the published studies focused on the role of physical activity in CVD prevention in persons with diabetes, and to discuss the implications of these studies' findings. Our review identified almost 100 studies published in the past decade relevant to this topic.
治疗心血管疾病 (CVD) 和糖尿病的成本巨大，而且预计在未来几年还会上升。身体活动不足和久坐行为是这些疾病的主要危险因素，每年估计有数百万人因此死亡。生活方式干预，特别是那些旨在提高身体活动水平的干预，对高危人群的糖尿病进展有显著的积极影响。尽管观察性研究和小型干预性研究表明，身体活动也可能预防糖尿病患者的 CVD，但这一观点并未得到更大规模的生活方式干预随机对照试验结果的支持。本综述的目的是提供已发表的关于身体活动在预防糖尿病患者 CVD 方面作用的研究概述，并讨论这些研究结果的意义。我们的综述确定了过去十年中与这一主题相关的近 100 项研究。
