Pinto Bernardine M, Dunsiger Shira, Waldemore Marissa
The Miriam Hospital, Providence, RI, USA.
W. Alpert Medical School of Brown University, Providence, RI, USA.
Psychooncology. 2013 Oct;22(10):2193-9. doi: 10.1002/pon.3272. Epub 2013 Mar 15.
Physical activity (PA) has been shown to provide health benefits for breast cancer patients. The effects of augmenting oncology healthcare provider (HCP) advice for PA with 3 months of telephone counseling versus contact control were evaluated in a randomized trial. Our goal in this secondary analysis was to examine the amount of PA (min/week) needed for psychosocial benefits among both groups.
After receiving brief HCP advice to become physically active, 192 women (age in years: mean = 60.0, SD = 9.9) who had completed treatment for Stage 0-IV breast cancer were randomized to telephone counseling to support PA (n = 106) or contact control (n = 86). Their PA, fatigue, physical functioning, and quality of life were assessed at baseline (before receiving HCP advice), 3, 6, and 12 months. A non-randomized design was used to examine the dose-response relationship between PA and psychosocial outcomes.
Exercising for at least 150 min/week at moderate intensity was associated with improved physical functioning (b = 5.9, SE = 2.9, p = 0.04) and quality of life (b = 3.6, SE = 1.9, p = 0.05) at 3 months. These relationships were not found at 6 and 12 months (p's > 0.05). However, women who reported at least 150 min/week of PA at both 3 and 6 months had significantly reduced fatigue (b = 1.3, SE = 0.7, p = 0.05) and improved physical functioning (b = 3.1, SE = 1.3, p = 0.02) and quality of life (b = 2.0, SE = 0.9, p = 0.02) compared with women who did not meet this criterion.
Women who exercised at recommended levels (at least 150 min/week) and sustained this level of activity for at least 6 months accrued psychosocial benefits.
体育活动（PA）已被证明对乳腺癌患者有益健康。在一项随机试验中，评估了通过3个月的电话咨询与接触控制来增强肿瘤医疗服务提供者（HCP）关于PA的建议的效果。我们在这项二次分析中的目标是研究两组中获得心理社会益处所需的PA量（分钟/周）。
在接受HCP关于进行体育活动的简短建议后，192名完成0-IV期乳腺癌治疗的女性（年龄：平均=60.0，标准差=9.9）被随机分为支持PA的电话咨询组（n=106）或接触控制组（n=86）。在基线（接受HCP建议之前）、3个月、6个月和12个月时评估她们的PA、疲劳、身体功能和生活质量。采用非随机设计来研究PA与心理社会结果之间的剂量反应关系。
在3个月时，每周至少进行150分钟中等强度的锻炼与身体功能改善（b=5.9，标准误=2.9，p=0.04）和生活质量改善（b=3.6，标准误=1.9，p=0.05）相关。在6个月和12个月时未发现这些关系（p>0.05）。然而，与未达到该标准的女性相比，在3个月和6个月时每周报告至少150分钟PA的女性疲劳明显减轻（b=1.3，标准误=0.7，p=0.05），身体功能改善（b=3.1，标准误=1.3，p=0.02），生活质量改善（b=2.0，标准误=0.9，p=0.02）。
以推荐水平（每周至少150分钟）进行锻炼并持续该活动水平至少6个月的女性获得了心理社会益处。
