链霉菌分化的孢子前阶段：现状与未来展望。
Pre-sporulation stages of Streptomyces differentiation: state-of-the-art and future perspectives.
机构信息
Área de Microbiología, Departamento de Biología Funcional, and IUBA, Facultad de Medicina, Universidad de Oviedo, Oviedo, Spain.
出版信息
FEMS Microbiol Lett. 2013 May;342(2):79-88. doi: 10.1111/1574-6968.12128. Epub 2013 Apr 12.
Abstract
Streptomycetes comprise very important industrial bacteria, producing two-thirds of all clinically relevant secondary metabolites. They are mycelial microorganisms with complex developmental cycles that include programmed cell death (PCD) and sporulation. Industrial fermentations are usually performed in liquid cultures (large bioreactors), conditions in which Streptomyces strains generally do not sporulate, and it was traditionally assumed that there was no differentiation. In this work, we review the current knowledge on Streptomyces pre-sporulation stages of Streptomyces differentiation.
摘要
链霉菌包含非常重要的工业细菌，产生所有临床相关的次级代谢物的三分之二。它们是菌丝体微生物，具有复杂的发育周期，包括程序性细胞死亡（PCD）和孢子形成。工业发酵通常在液体培养（大型生物反应器）中进行，在这种条件下，链霉菌菌株通常不会形成孢子，并且传统上认为没有分化。在这项工作中，我们回顾了链霉菌分化的链霉菌预孢子形成阶段的现有知识。
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