Department of Microbiology, Chung-Ang University College of Medicine, Seoul, South Korea.
Arch Virol. 2013 Aug;158(8):1795-803. doi: 10.1007/s00705-013-1662-2. Epub 2013 Mar 17.
Three human rotavirus G9P[8] strains, RVA/Human-tc/KOR/CAU05-202/2005/G9P[8], RVA/Human-tc/KOR/CAU09-371/2009/G9P[8], and RVA/Human-tc/KOR/CAU09-376/2009/G9P[8], were isolated from female pediatric patients with diarrhea from 2005 to 2009 using a cell culture system, and their complete genomic sequences were analyzed. The 11 gene segments of the three Korean strains possessed the G9-P[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1 genotype, which is closely related to the Wa-like genotype 1 constellation. Interestingly, the NSP2 and the NSP3 genes of strain RVA/Human-tc/KOR/CAU09-376/2009/G9P[8] were related to the G9 porcine or human-porcine reassortant strains, providing evidence for porcine-to-human interspecies transmission.
从 2005 年至 2009 年，通过细胞培养系统从患有腹泻的女性儿科患者中分离出了三株人类轮状病毒 G9P[8]株，RVA/Human-tc/KOR/CAU05-202/2005/G9P[8]、RVA/Human-tc/KOR/CAU09-371/2009/G9P[8]和 RVA/Human-tc/KOR/CAU09-376/2009/G9P[8]，并对其完整基因组序列进行了分析。这三株韩国分离株的 11 个基因片段具有 G9-P[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1 基因型，与 Wa 样基因型 1 组成密切相关。有趣的是，RVA/Human-tc/KOR/CAU09-376/2009/G9P[8]株的 NSP2 和 NSP3 基因与 G9 猪或人-猪重组株有关，为猪与人种间传播提供了证据。
