Ghassemi Fariba, Ghadimi Hadi, Amoli Fahimeh Asadi, Esfahani Mohammad Riazi, Tavakoli Vida, Fariba Ghassemi
Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Qazvin Square, 1336616351, Tehran, Iran,
Int Ophthalmol. 2014 Feb;34(1):137-40. doi: 10.1007/s10792-013-9753-3. Epub 2013 Mar 16.
A 4-year-old boy presented with unilateral endophthalmitis and echography revealed an abscess in the vitreous cavity. A pars plana vitrectomy with intravitreal antibiotic injections was performed with a presumed diagnosis of endophthalmitis; however, the patient returned after 10 days with fibrin reaction in the anterior chamber, iris nodules and cataract. The vitreous sample from the vitrectomy showed Toxoplasma gondii parasite, so he was treated with intravitreal clindamycin and lensectomy. The postoperative fundus examination revealed multifocal white patches with calcified deposits and cytology proved the diagnosis of retinoblastoma. Enucleation was performed in addition to systemic chemotherapy. To our knowledge, this is the first reported case of the coexistence of retinoblastoma and ocular toxoplasmosis.
一名4岁男孩出现单侧眼内炎，超声检查显示玻璃体腔有脓肿。在假定诊断为眼内炎的情况下进行了玻璃体切除术并玻璃体内注射抗生素；然而，患者在10天后复诊时出现前房纤维蛋白反应、虹膜结节和白内障。玻璃体切除术中获取的玻璃体样本显示有刚地弓形虫寄生虫，因此对他进行了玻璃体内注射克林霉素和晶状体切除术治疗。术后眼底检查发现有多灶性白色斑块伴钙化沉积物，细胞学检查证实为视网膜母细胞瘤。除全身化疗外还进行了眼球摘除术。据我们所知，这是首次报道的视网膜母细胞瘤与眼弓形虫病并存的病例。
